Direct Asymmetric Ruthenium-Catalyzed Reductive Amination of Alkyl–Aryl Ketones with Ammonia and Hydrogen

The asymmetric ruthenium-catalyzed reductive amination employing ammonia and hydrogen to primary amines is described. Here we demonstrate the capability of our catalyst to perform a chemo- and enantioselective process while using simple ammonia gas as a reagent, one of the most attractive and indust...

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Veröffentlicht in:	Journal of the American Chemical Society 2018-01, Vol.140 (1), p.355-361
Hauptverfasser:	Gallardo-Donaire, Joan, Hermsen, Marko, Wysocki, Jedrzej, Ernst, Martin, Rominger, Frank, Trapp, Oliver, Hashmi, A. Stephen K, Schäfer, Ansgar, Comba, Peter, Schaub, Thomas
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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