$The fractional laser‐induced coagulation zone characterized over time by laser scanning confocal microscopy—A proof of concept study$

The fractional laser‐induced coagulation zone characterized over time by laser scanning confocal microscopy—A proof of concept study

Background Ablative fractional laser (AFXL) is an acknowledged technique to increase uptake of topical agents in skin. Micro thermal ablation zones (MAZs) consist of ablated vertical channels surrounded by a coagulation zone (CZ). Laser scanning confocal microscopy (LSCM) images individual MAZs at 7...

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Veröffentlicht in:	Lasers in surgery and medicine 2018-01, Vol.50 (1), p.70-77
Hauptverfasser:	Banzhaf, Christina A., Lin, Lynlee L., Dang, Nhung, Freeman, Michael, Haedersdal, Merete, Prow, Tarl W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ablation Coagulation Compartments Confocal microscopy Dermis Drugs Epidermis Feasibility studies Fluorescein Fluorescence Fluorescence confocal microscopy fluorescence intensity Humans imaging Kinetics Laser Coagulation - methods Lasers Lasers, Solid-State - therapeutic use micro thermal ablation zone Microscopy Microscopy, Confocal Proof of Concept Study Reflectance reflectance confocal microscopy Skin Skin - diagnostic imaging Skin - radiation effects Sodium sodium fluorescein Stratum corneum Thickness measurement Tissue Culture Techniques topical drug delivery
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