The role of zinc in the treatment of acne: A review of the literature
Acne vulgaris is a chronic disease of the pilosebaceous units presenting as inflammatory or noninflammatory lesions in individuals of all ages. The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents,...
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| Veröffentlicht in: | Dermatologic therapy 2018-01, Vol.31 (1), p.e12576-n/a |
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| creator | Cervantes, Jessica Eber, Ariel E. Perper, Marina Nascimento, Vanessa M. Nouri, Keyvan Keri, Jonette E. |
| description | Acne vulgaris is a chronic disease of the pilosebaceous units presenting as inflammatory or noninflammatory lesions in individuals of all ages. The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents, retinoids, and comedolytics. Additionally, systemic treatments are available for more severe or resistant forms of acne. Nevertheless, these treatments have shown to induce a wide array of adverse effects, including dryness, peeling, erythema, and even fetal defects and embolic events. Zinc is a promising alternative to other acne treatments owing to its low cost, efficacy, and lack of systemic side effects. In this literature review, we evaluate the effectiveness and side‐effect profiles of various formulations of zinc used to treat acne. |
| doi_str_mv | 10.1111/dth.12576 |
| format | Article |
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The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents, retinoids, and comedolytics. Additionally, systemic treatments are available for more severe or resistant forms of acne. Nevertheless, these treatments have shown to induce a wide array of adverse effects, including dryness, peeling, erythema, and even fetal defects and embolic events. Zinc is a promising alternative to other acne treatments owing to its low cost, efficacy, and lack of systemic side effects. 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The current standard of treatment includes topical formulations in the forms of washes, gels, lotions, and creams such as antibiotics, antibacterial agents, retinoids, and comedolytics. Additionally, systemic treatments are available for more severe or resistant forms of acne. Nevertheless, these treatments have shown to induce a wide array of adverse effects, including dryness, peeling, erythema, and even fetal defects and embolic events. Zinc is a promising alternative to other acne treatments owing to its low cost, efficacy, and lack of systemic side effects. In this literature review, we evaluate the effectiveness and side‐effect profiles of various formulations of zinc used to treat acne.</description><subject>acne</subject><subject>Acne Vulgaris - diagnosis</subject><subject>Acne Vulgaris - drug therapy</subject><subject>Administration, Cutaneous</subject><subject>Administration, Oral</subject><subject>Dermatologic Agents - administration & dosage</subject><subject>Dermatologic Agents - adverse effects</subject><subject>Drug Combinations</subject><subject>Female</subject><subject>Gluconates - administration & dosage</subject><subject>Gluconates - adverse effects</subject><subject>Humans</subject><subject>inflammatory disorders</subject><subject>Male</subject><subject>Skin - drug effects</subject><subject>Skin - pathology</subject><subject>systemic therapy</subject><subject>therapy topical</subject><subject>Treatment Outcome</subject><subject>zinc</subject><subject>Zinc Acetate - administration & dosage</subject><subject>Zinc Acetate - adverse effects</subject><subject>Zinc Oxide - administration & dosage</subject><subject>Zinc Sulfate - administration & dosage</subject><subject>Zinc Sulfate - adverse effects</subject><issn>1396-0296</issn><issn>1529-8019</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kD1PwzAQhi0EoqUw8AdQRhhC_ZHYNVtVCkWqxFJmy4nPalA-ip1QlV-PQwobt9zp7tFz0ovQNcH3JNTUtNt7QlPBT9CYpFTGM0zkaZiZ5DGmko_QhffvGBMqGTlHIyqJZBzTMVputhC5poSosdFXUedRUUdt2LUOdFtB3fYHndfwEM0jB58F7PtNj5RFC063nYNLdGZ16eHq2Cfo7Wm5Wazi9evzy2K-jvPwjcdMSyKEkEliEyuSDAyjBs94KqmkhBhNeIYTITPOrBEgDRUWOAYz4zYxgrEJuh28O9d8dOBbVRU-h7LUNTSdV0QKwhOGeRrQuwHNXeO9A6t2rqi0OyiCVZ-aCqmpn9QCe3PUdlkF5o_8jSkA0wHYFyUc_jepx81qUH4DWzN0Lw</recordid><startdate>201801</startdate><enddate>201801</enddate><creator>Cervantes, Jessica</creator><creator>Eber, Ariel E.</creator><creator>Perper, Marina</creator><creator>Nascimento, Vanessa M.</creator><creator>Nouri, Keyvan</creator><creator>Keri, Jonette E.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0001-6697-3145</orcidid><orcidid>https://orcid.org/0000-0003-4916-6434</orcidid></search><sort><creationdate>201801</creationdate><title>The role of zinc in the treatment of acne: A review of the literature</title><author>Cervantes, Jessica ; 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| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | acne Acne Vulgaris - diagnosis Acne Vulgaris - drug therapy Administration, Cutaneous Administration, Oral Dermatologic Agents - administration & dosage Dermatologic Agents - adverse effects Drug Combinations Female Gluconates - administration & dosage Gluconates - adverse effects Humans inflammatory disorders Male Skin - drug effects Skin - pathology systemic therapy therapy topical Treatment Outcome zinc Zinc Acetate - administration & dosage Zinc Acetate - adverse effects Zinc Oxide - administration & dosage Zinc Sulfate - administration & dosage Zinc Sulfate - adverse effects |
| title | The role of zinc in the treatment of acne: A review of the literature |
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