Upregulation of the miR-515 cluster in the MCF7 breast cancer cell line by epigenetic therapy

Introduction. In cancer, hypermethylation of promoter CpG islands has been shown to down regulate the transcription of tumor suppressor genes. Treatment by inhibitors of DNA methyltransferease (DNMTi) can reactivate the transcription of silenced genes and restore normal cell growth and differentiati...

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Veröffentlicht in:	APMIS : acta pathologica, microbiologica et immunologica Scandinavica microbiologica et immunologica Scandinavica, 2008-05, Vol.116 (5), p.437-437
Hauptverfasser:	Hother, C, Cortez, C, Miranda, T, Yoo, C, Workman, C, Jones, P A, Groenbaek, K
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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