Curcumin (diferuloylmethane) alters the expression profiles of microRNAs in human pancreatic cancer cells

Background: A major challenge in cancer chemotherapy has been developing safe and clinically efficacious chemotherapeutic agents. With its low toxicity profile, curcumin (diferuloylmethane), a naturally occurring flavinoid derived from the rhizome of Curcuma longa , has great promise. In vitro and i...

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Veröffentlicht in:	Molecular cancer therapeutics 2008-03, Vol.7 (3), p.464-473
Hauptverfasser:	Sun, Michael, Estrov, Zeev, Ji, Yuan, Coombes, Kevin R, Harris, David H, Kurzrock, Razelle
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer Cell Line, Tumor Chemotherapy Curcuma longa Curcumin Curcumin - pharmacology Flow Cytometry Gene Expression Profiling Humans Microarray MicroRNA MicroRNAs - genetics Pancreatic cancer Pancreatic Neoplasms - genetics Pancreatic Neoplasms - pathology Polymerase Chain Reaction
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