Successful simplification of protease inhibitor-based HAART with triple nucleoside regimens in children vertically infected with HIV

To assess the virological, immunological and metabolic effects of switching from an efficacious first-line protease inhibitor (PI)-based HAART to a simplified triple nucleoside reverse transcriptase inhibitor (NRTI) regimen in children vertically infected with HIV. Prospective, open-label, before-af...

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Veröffentlicht in:	AIDS (London) 2007-11, Vol.21 (18), p.2465-2472
Hauptverfasser:	PALMA, Paolo, LUISA ROMITI, Maria, CANCRINI, Caterina, PENSIEROSO, Simone, MONTESANO, Carla, SANTUCCI, Marilina B, BERNARDI, Stefania, MARTINO, Alessandra M, ROSSI, Paolo, CASTELLI-GATTINARA, Guido
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral Therapy, Highly Active - adverse effects Antiretroviral Therapy, Highly Active - methods Antiviral agents Biological and medical sciences CD8-Positive T-Lymphocytes - immunology Child Child, Preschool Cholesterol - blood Epidemiologic Methods Female HIV Infections - drug therapy HIV Infections - immunology HIV Infections - transmission HIV Infections - virology HIV Protease Inhibitors - adverse effects HIV Protease Inhibitors - therapeutic use HIV-1 Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious Disease Transmission, Vertical Infectious diseases Male Medical sciences Patient Compliance Pharmacology. Drug treatments Prospective Studies Receptors, Antigen, T-Cell, alpha-beta - analysis Reverse Transcriptase Inhibitors - adverse effects Reverse Transcriptase Inhibitors - therapeutic use Treatment Outcome Triglycerides - blood Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids
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