A significant therapeutic effect of immunoglobulins administered alone, or in combination with conventional chemotherapy, in experimental pulmonary tuberculosis caused by drug-sensitive or drug-resistant strains

The recommended chemotherapy for drug-sensitive tuberculosis (TB) consists of four different antibiotics administrated for 6 months. This long treatment leads to significant compliance problems and consequently to recrudescence of the disease and to the development of multidrug-resistant (MDR) strai...

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Veröffentlicht in:	Pathogens and disease 2017-12, Vol.75 (9)
Hauptverfasser:	Olivares, Nesty, Rodriguez, Yadira, Zatarain-Barron, Zyanya Lucia, Marquina, Brenda, Mata-Espinosa, Dulce, Barrios-Payán, Jorge, Parada, Cristina, Moguel, Bárbara, Espitia-Pinzón, Clara, Estrada, Iris, Hernandez-Pando, Rogelio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antitubercular Agents - administration & dosage Bacterial Load Combined Modality Therapy - methods Disease Models, Animal Drug Therapy - methods Immunoglobulins, Intravenous - administration & dosage Immunotherapy - methods Lung - microbiology Male Mice, Inbred BALB C Mycobacterium tuberculosis - drug effects Mycobacterium tuberculosis - isolation & purification Treatment Outcome Tuberculosis, Pulmonary - drug therapy
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