Structural-Based Engineering for Transferases to Improve the Industrial Production of 5′-Nucleotides

The existence of a flexible region for substrate recognition by an enzyme was first discovered through a structure comparison study among ribonuclease T1–related molecules, including intact molecules, intact molecules complexed with 2′-guanylic acid (GMP), and carboxymethylated molecules complexed w...

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Veröffentlicht in:Bulletin of the Chemical Society of Japan 2007-02, Vol.80 (2), p.276-286
Hauptverfasser: Suzuki, Ei-ichiro, Ishikawa, Kohki, Mihara, Yasuhiro, Shimba, Nobuhisa, Asano, Yasuhisa
Format: Artikel
Sprache:eng
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