Attentional Control and Brain Metabolite Levels in Methamphetamine Abusers

Background Methamphetamine abuse is associated with neurotoxicity to frontostriatal brain regions with concomitant deleterious effects on cognitive processes. Methods By using a computerized measure of selective attention and single-voxel proton magnetic resonance spectroscopy, we examined the relat...

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Veröffentlicht in:	Biological psychiatry (1969) 2007-06, Vol.61 (11), p.1272-1280
Hauptverfasser:	Salo, Ruth, Nordahl, Thomas E, Natsuaki, Yutaka, Leamon, Martin H, Galloway, Gantt P, Waters, Christy, Moore, Charles D, Buonocore, Michael H
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Amphetamine-Related Disorders - metabolism Amphetamine-Related Disorders - psychology Anterior cingulate cortex attention Attention - drug effects Biological and medical sciences Brain Chemistry - drug effects Central Nervous System Stimulants Choline - metabolism Cognition - physiology Creatine - metabolism Female Humans Image Processing, Computer-Assisted imaging Magnetic Resonance Imaging Magnetic Resonance Spectroscopy Male Medical sciences Methamphetamine MRS NAA Neuropharmacology Neuropsychological Tests Pharmacology. Drug treatments Photic Stimulation Psychiatry Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease) Psychology. Psychoanalysis. Psychiatry Psychomotor Performance - drug effects Psychopathology. Psychiatry Psychopharmacology Reaction Time - physiology Smoking - metabolism Smoking - psychology Stroop Visual Cortex - drug effects Visual Cortex - metabolism
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