Lymphocyte count in peripheral blood is not associated with the level of clinical response to treatment with fingolimod

Fingolimod is an efficient and safe drug for treating relapsing-remitting multiple sclerosis (RRMS). In vivo, fingolimod is phosphorylated and binds to “sphingosine-1-phosphate”(S1P) receptors that are expressed in a wide range of cells, including lymphocytes. Under the effect of fingolimod, lymphoc...

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Veröffentlicht in:	Multiple sclerosis and related disorders 2018-01, Vol.19, p.105-108
Hauptverfasser:	Fragoso, Yara Dadalti, Spelman, Tim, Boz, Cavit, Alroughani, Raed, Lugaresi, Alessandra, Vucic, Steve, Butzkueven, Helmut, Terzi, Murat, Havrdova, Eva, Horakova, Dana, Granella, Franco, Olascoaga, Javier, Sánchez-Menoyo, José Luis, Pucci, Eugenio, Barnett, Michael, Brooks, Joseph Bruno B., Haartsen, Jodi
Format:	Artikel
Sprache:	eng
Schlagworte:	Disability Fingolimod Lymphocytes Multiple sclerosis Relapses
Online-Zugang:	Volltext
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