In vitro toxicity evaluation of single walled carbon nanotubes on human A549 lung cells

This paper describes the in vitro cytotoxicity assessment of single walled carbon nanotubes (SWCNT) on A549 cells, a human lung cell line. Cellular viability was determined using the alamar blue (AB), neutral red (NR) and MTT assays, which evaluated metabolic, lysosomal and mitochondrial activity re...

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Veröffentlicht in:	Toxicology in vitro 2007-04, Vol.21 (3), p.438-448
Hauptverfasser:	Davoren, Maria, Herzog, Eva, Casey, Alan, Cottineau, Benjamin, Chambers, Gordon, Byrne, Hugh J., Lyng, Fiona M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenylate Kinase - metabolism Cell Line Cell Nucleus - drug effects Cell Nucleus - ultrastructure Cell Survival - drug effects Culture Media, Conditioned - chemistry Cytoplasm - drug effects Cytoplasm - ultrastructure Cytotoxicity Dose-Response Relationship, Drug Epithelial Cells - drug effects Epithelial Cells - metabolism Epithelial Cells - pathology Foetal bovine serum Formazans - metabolism Humans Indicators and Reagents - metabolism Interleukin-8 - metabolism Lamellar bodies Lung - drug effects Lung - metabolism Lung - pathology Microscopy, Electron, Transmission Nanotechnology Nanotubes, Carbon - chemistry Nanotubes, Carbon - toxicity Nanotubes, Carbon - ultrastructure Necrosis - chemically induced Neutral Red - metabolism Oxazines - metabolism Quartz - metabolism Quartz - toxicity Rosaniline Dyes - metabolism Single walled carbon nanotubes TEM Tetrazolium Salts - metabolism Xanthenes - metabolism
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