Inhibitory Effects of Honokiol on the Voltage-Gated Potassium Channels in Freshly Isolated Mouse Dorsal Root Ganglion Neurons

Voltage-gated potassium (K V ) currents, subdivided into rapidly inactivating A-type currents ( I A ) and slowly inactivating delayed rectifier currents ( I K ), play a fundamental role in modulating pain by controlling neuronal excitability. The effects of Honokiol (Hon), a natural biphenolic compo...

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Veröffentlicht in:	Neurochemical research 2018-02, Vol.43 (2), p.450-457
Hauptverfasser:	Sheng, Anqi, Zhang, Yan, Li, Guang, Zhang, Guangqin
Format:	Artikel
Sprache:	eng
Schlagworte:	Biochemistry Biomedical and Life Sciences Biomedicine Cell Biology Channels Deactivation Dorsal root ganglia Electric potential Excitability Inactivation Inflammation Neurochemistry Neurology Neurons Neurosciences Original Paper Pain Pain perception Potassium Potassium channels (voltage-gated)
Online-Zugang:	Volltext
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