Deletion of GIRK2 subunit containing GIRK channels of neurons expressing dopamine transporter decrease immobility time on forced swimming in mice

•Generation of GIRK2 cKO mice with specific deletion of GIRK2 subunit in neurons expressing dopamine transporter.•GIRK2 cKO mice reduced depression-like behaviours.•GIRK2 cKO mice mimic the effects of antitussives in the forced swimming. We previously reported that non-narcotic antitussives possessi...

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Veröffentlicht in:	Neuroscience letters 2018-02, Vol.665, p.140-146
Hauptverfasser:	Honda, Ikutaro, Araki, Kimi, Honda, Sokichi, Soeda, Fumio, Shin, Min-Chul, Misumi, Shogo, Yamamura, Ken-ichi, Takahama, Kazuo
Format:	Artikel
Sprache:	eng
Schlagworte:	Antidepressant Antitussive GIRK2
Online-Zugang:	Volltext
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