The key role of extracellular vesicles in the metastatic process

Extracellular vesicles (EVs), including exosomes, have a key role in the paracrine communication between organs and compartments. EVs shuttle virtually all types of biomolecules such as proteins, lipids, nucleic acids, metabolites and even pharmacological compounds. Their ability to transfer their b...

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Veröffentlicht in:	Biochimica et biophysica acta 2018-01, Vol.1869 (1), p.64-77
Hauptverfasser:	Zhao, Hongyun, Achreja, Abhinav, Iessi, Elisabetta, Logozzi, Mariantonia, Mizzoni, Davide, Di Raimo, Rossella, Nagrath, Deepak, Fais, Stefano
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Communication - physiology Cell Transformation, Neoplastic - pathology Disease Progression Exosomes Extracellular vesicles Extracellular Vesicles - physiology Humans Metastasis Metastatic niche Neoplasm Metastasis - pathology Neoplasms - pathology Tumor metabolism Tumor microenvironment Tumor Microenvironment - physiology
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