Exome sequencing of synchronously resected primary colorectal tumours and colorectal liver metastases to inform oncosurgical management

Next generation sequencing technology has facilitated mapping of the colorectal cancer genotype and furthered our understanding of metastogenesis. The aim of this study was to investigate for conserved and different mutations in the exomes of synchronously resected primary colorectal tumour and live...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	European journal of surgical oncology 2018-01, Vol.44 (1), p.115-121
Hauptverfasser:	Sutton, P.A., Jithesh, P.V., Jones, R.P., Evans, J.P., Vimalachandran, D., Malik, H.Z., Park, B.K., Goldring, C.E., Palmer, D.H., Kitteringham, N.R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma - genetics Adenocarcinoma - secondary Adenocarcinoma - therapy Aged Chemotherapy, Adjuvant Colectomy - methods Colorectal cancer Colorectal Neoplasms - genetics Colorectal Neoplasms - pathology Colorectal Neoplasms - therapy Combined Modality Therapy DNA, Neoplasm - genetics Exome Female Gene Frequency Hepatectomy High-Throughput Nucleotide Sequencing - methods Humans Liver Neoplasms - genetics Liver Neoplasms - secondary Liver Neoplasms - therapy Male Middle Aged Mutation Neoplasm Metastasis Next generation sequencing Stage IV Synchronous resection Treatment Outcome
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!