Can we increase speed and efficacy of antidepressant treatments? Part I: General aspects and monoamine-based strategies

Major depressive disorder (MDD) is a severe psychiatric syndrome with high prevalence and socioeconomic impact. Current antidepressant treatments are based on the blockade of serotonin (5-hydroxytryptamine, 5-HT) and/or noradrenaline transporters. These drugs show slow onset of clinical action and l...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European neuropsychopharmacology 2018-04, Vol.28 (4), p.445-456
Hauptverfasser:	Artigas, Francesc, Bortolozzi, Analia, Celada, Pau
Format:	Artikel
Sprache:	eng
Schlagworte:	5-hydroxytryptamine (serotonin) receptors Animals Antidepressant drugs Antidepressive Agents - pharmacology Antidepressive Agents - therapeutic use Autoreceptors Biogenic Monoamines - metabolism Depressive Disorder, Major - drug therapy Depressive Disorder, Major - metabolism Humans Multi-target agents Neurotransmitter Agents - pharmacology Neurotransmitter Agents - therapeutic use
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!