Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey
Aims To describe the associations of frailty with diabetes mellitus and related conditions in older adults. Methods We conducted a cross-sectional analysis of a representative sample of older adults ( n = 5379). We generated a 35-item frailty index (FI) and obtained information on diabetes and rela...
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| Veröffentlicht in: | Aging clinical and experimental research 2018-08, Vol.30 (8), p.935-941 |
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| creator | Castrejón-Pérez, Roberto C. Aguilar-Salinas, Carlos A. Gutiérrez-Robledo, Luis M. Cesari, Matteo Pérez-Zepeda, Mario U. |
| description | Aims
To describe the associations of frailty with diabetes mellitus and related conditions in older adults.
Methods
We conducted a cross-sectional analysis of a representative sample of older adults (
n
= 5379). We generated a 35-item frailty index (FI) and obtained information on diabetes and related conditions (peripheral neuropathy, lower limb amputation, diabetic coma, number of physician visits due to diabetes-related conditions, all-cause hospitalizations in the past year, years since diabetes diagnosis, and type of treatment). Logistic and Poisson regression models were used to determine the associations between frailty and diabetes and its complications.
Results
The mean age was 70.3 years (± 7.8); 54.7% were women. Those with an FI ≤ 0.082 composed the reference group. Multivariate analysis showed an OR of 2.32 (95% CI 1.93–2.73,
p
|
| doi_str_mv | 10.1007/s40520-017-0852-2 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_1969922457</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1969922457</sourcerecordid><originalsourceid>FETCH-LOGICAL-c372t-ddf8308fe9fdb63e6426c142e62c6b2296cbdad5dba8b68cce8b39d9f64c0933</originalsourceid><addsrcrecordid>eNp1kc2OFCEUhYnROGPrA7gxJG5cDApUNVW4MxNHTca4mT3h51Y3k2pouVWj_WY-nlT3-BMTV3Av3z0HOIQ8F_y14Lx7gy1fS8646Bjv15LJB-RcdLXTN0I__Gt_Rp4g3nLeilo8JmdSi150qjsnP66KjeN0uKAhWgcT4AW1KdBpC9TndAdlA8kDzQP125JT9BVEsAg0pkpSuwFWYLQThGUgxCnm9JZaus_7ubZrxVzFA03H4lsMVblkRIbgl44dq44dDxhxsVmcP8P36Kt4mqdyFDzeaQt2nLYU53IHh6fk0WBHhGf364rcXL2_ufzIrr98-HT57pr5ppMTC2HoG94PoIfgVAOqlcqLVoKSXjkptfIu2LAOzvZO9d5D7xod9KBaz3XTrMirk-y-5K8z4GR2ET2Mo02QZzRCK62lbNddRV_-g97mudSXoZFNq4WopKiUOFHHPygwmH2JO1sORnCzpGpOqZqaqllSrcMr8uJeeXY7CL8nfsVYAXkCsB6lDZQ_1v9X_QmjCbFK</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2349116991</pqid></control><display><type>article</type><title>Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey</title><source>SpringerLink Journals - AutoHoldings</source><creator>Castrejón-Pérez, Roberto C. ; Aguilar-Salinas, Carlos A. ; Gutiérrez-Robledo, Luis M. ; Cesari, Matteo ; Pérez-Zepeda, Mario U.</creator><creatorcontrib>Castrejón-Pérez, Roberto C. ; Aguilar-Salinas, Carlos A. ; Gutiérrez-Robledo, Luis M. ; Cesari, Matteo ; Pérez-Zepeda, Mario U.</creatorcontrib><description>Aims
To describe the associations of frailty with diabetes mellitus and related conditions in older adults.
Methods
We conducted a cross-sectional analysis of a representative sample of older adults (
n
= 5379). We generated a 35-item frailty index (FI) and obtained information on diabetes and related conditions (peripheral neuropathy, lower limb amputation, diabetic coma, number of physician visits due to diabetes-related conditions, all-cause hospitalizations in the past year, years since diabetes diagnosis, and type of treatment). Logistic and Poisson regression models were used to determine the associations between frailty and diabetes and its complications.
Results
The mean age was 70.3 years (± 7.8); 54.7% were women. Those with an FI ≤ 0.082 composed the reference group. Multivariate analysis showed an OR of 2.32 (95% CI 1.93–2.73,
p
< 0.001) for the association between diabetes and frailty. People who were hospitalized for any cause during the previous year, those receiving both insulin and an oral compound to manage diabetes, and those with peripheral neuropathy showed ORs of 2.32 (95% CI 1.69–3.18,
p
< 0.001), 5.6 (95% CI 1.58–19.8,
p
= 0.008), and 2.02 (95% CI 1.42–2.86,
p
< 0.001), respectively, for being in the most frail group.
Conclusions
People with diabetes have higher frailty scores. Furthermore, older adults with diabetes and higher burden of frailty have more diabetes-related complications.</description><identifier>ISSN: 1720-8319</identifier><identifier>ISSN: 1594-0667</identifier><identifier>EISSN: 1720-8319</identifier><identifier>DOI: 10.1007/s40520-017-0852-2</identifier><identifier>PMID: 29181767</identifier><language>eng</language><publisher>Cham: Springer International Publishing</publisher><subject>Cross-sectional studies ; Diabetes ; Frailty ; Geriatrics/Gerontology ; Medicine ; Medicine & Public Health ; Older people ; Original Article ; Peripheral neuropathy</subject><ispartof>Aging clinical and experimental research, 2018-08, Vol.30 (8), p.935-941</ispartof><rights>Springer International Publishing AG, part of Springer Nature 2017</rights><rights>Aging Clinical and Experimental Research is a copyright of Springer, (2017). All Rights Reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c372t-ddf8308fe9fdb63e6426c142e62c6b2296cbdad5dba8b68cce8b39d9f64c0933</citedby><cites>FETCH-LOGICAL-c372t-ddf8308fe9fdb63e6426c142e62c6b2296cbdad5dba8b68cce8b39d9f64c0933</cites><orcidid>0000-0003-4374-976X</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://link.springer.com/content/pdf/10.1007/s40520-017-0852-2$$EPDF$$P50$$Gspringer$$H</linktopdf><linktohtml>$$Uhttps://link.springer.com/10.1007/s40520-017-0852-2$$EHTML$$P50$$Gspringer$$H</linktohtml><link.rule.ids>314,780,784,27923,27924,41487,42556,51318</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29181767$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Castrejón-Pérez, Roberto C.</creatorcontrib><creatorcontrib>Aguilar-Salinas, Carlos A.</creatorcontrib><creatorcontrib>Gutiérrez-Robledo, Luis M.</creatorcontrib><creatorcontrib>Cesari, Matteo</creatorcontrib><creatorcontrib>Pérez-Zepeda, Mario U.</creatorcontrib><title>Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey</title><title>Aging clinical and experimental research</title><addtitle>Aging Clin Exp Res</addtitle><addtitle>Aging Clin Exp Res</addtitle><description>Aims
To describe the associations of frailty with diabetes mellitus and related conditions in older adults.
Methods
We conducted a cross-sectional analysis of a representative sample of older adults (
n
= 5379). We generated a 35-item frailty index (FI) and obtained information on diabetes and related conditions (peripheral neuropathy, lower limb amputation, diabetic coma, number of physician visits due to diabetes-related conditions, all-cause hospitalizations in the past year, years since diabetes diagnosis, and type of treatment). Logistic and Poisson regression models were used to determine the associations between frailty and diabetes and its complications.
Results
The mean age was 70.3 years (± 7.8); 54.7% were women. Those with an FI ≤ 0.082 composed the reference group. Multivariate analysis showed an OR of 2.32 (95% CI 1.93–2.73,
p
< 0.001) for the association between diabetes and frailty. People who were hospitalized for any cause during the previous year, those receiving both insulin and an oral compound to manage diabetes, and those with peripheral neuropathy showed ORs of 2.32 (95% CI 1.69–3.18,
p
< 0.001), 5.6 (95% CI 1.58–19.8,
p
= 0.008), and 2.02 (95% CI 1.42–2.86,
p
< 0.001), respectively, for being in the most frail group.
Conclusions
People with diabetes have higher frailty scores. Furthermore, older adults with diabetes and higher burden of frailty have more diabetes-related complications.</description><subject>Cross-sectional studies</subject><subject>Diabetes</subject><subject>Frailty</subject><subject>Geriatrics/Gerontology</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Older people</subject><subject>Original Article</subject><subject>Peripheral neuropathy</subject><issn>1720-8319</issn><issn>1594-0667</issn><issn>1720-8319</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNp1kc2OFCEUhYnROGPrA7gxJG5cDApUNVW4MxNHTca4mT3h51Y3k2pouVWj_WY-nlT3-BMTV3Av3z0HOIQ8F_y14Lx7gy1fS8646Bjv15LJB-RcdLXTN0I__Gt_Rp4g3nLeilo8JmdSi150qjsnP66KjeN0uKAhWgcT4AW1KdBpC9TndAdlA8kDzQP125JT9BVEsAg0pkpSuwFWYLQThGUgxCnm9JZaus_7ubZrxVzFA03H4lsMVblkRIbgl44dq44dDxhxsVmcP8P36Kt4mqdyFDzeaQt2nLYU53IHh6fk0WBHhGf364rcXL2_ufzIrr98-HT57pr5ppMTC2HoG94PoIfgVAOqlcqLVoKSXjkptfIu2LAOzvZO9d5D7xod9KBaz3XTrMirk-y-5K8z4GR2ET2Mo02QZzRCK62lbNddRV_-g97mudSXoZFNq4WopKiUOFHHPygwmH2JO1sORnCzpGpOqZqaqllSrcMr8uJeeXY7CL8nfsVYAXkCsB6lDZQ_1v9X_QmjCbFK</recordid><startdate>20180801</startdate><enddate>20180801</enddate><creator>Castrejón-Pérez, Roberto C.</creator><creator>Aguilar-Salinas, Carlos A.</creator><creator>Gutiérrez-Robledo, Luis M.</creator><creator>Cesari, Matteo</creator><creator>Pérez-Zepeda, Mario U.</creator><general>Springer International Publishing</general><general>Springer Nature B.V</general><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-4374-976X</orcidid></search><sort><creationdate>20180801</creationdate><title>Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey</title><author>Castrejón-Pérez, Roberto C. ; Aguilar-Salinas, Carlos A. ; Gutiérrez-Robledo, Luis M. ; Cesari, Matteo ; Pérez-Zepeda, Mario U.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c372t-ddf8308fe9fdb63e6426c142e62c6b2296cbdad5dba8b68cce8b39d9f64c0933</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Cross-sectional studies</topic><topic>Diabetes</topic><topic>Frailty</topic><topic>Geriatrics/Gerontology</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Older people</topic><topic>Original Article</topic><topic>Peripheral neuropathy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Castrejón-Pérez, Roberto C.</creatorcontrib><creatorcontrib>Aguilar-Salinas, Carlos A.</creatorcontrib><creatorcontrib>Gutiérrez-Robledo, Luis M.</creatorcontrib><creatorcontrib>Cesari, Matteo</creatorcontrib><creatorcontrib>Pérez-Zepeda, Mario U.</creatorcontrib><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Aging clinical and experimental research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Castrejón-Pérez, Roberto C.</au><au>Aguilar-Salinas, Carlos A.</au><au>Gutiérrez-Robledo, Luis M.</au><au>Cesari, Matteo</au><au>Pérez-Zepeda, Mario U.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey</atitle><jtitle>Aging clinical and experimental research</jtitle><stitle>Aging Clin Exp Res</stitle><addtitle>Aging Clin Exp Res</addtitle><date>2018-08-01</date><risdate>2018</risdate><volume>30</volume><issue>8</issue><spage>935</spage><epage>941</epage><pages>935-941</pages><issn>1720-8319</issn><issn>1594-0667</issn><eissn>1720-8319</eissn><abstract>Aims
To describe the associations of frailty with diabetes mellitus and related conditions in older adults.
Methods
We conducted a cross-sectional analysis of a representative sample of older adults (
n
= 5379). We generated a 35-item frailty index (FI) and obtained information on diabetes and related conditions (peripheral neuropathy, lower limb amputation, diabetic coma, number of physician visits due to diabetes-related conditions, all-cause hospitalizations in the past year, years since diabetes diagnosis, and type of treatment). Logistic and Poisson regression models were used to determine the associations between frailty and diabetes and its complications.
Results
The mean age was 70.3 years (± 7.8); 54.7% were women. Those with an FI ≤ 0.082 composed the reference group. Multivariate analysis showed an OR of 2.32 (95% CI 1.93–2.73,
p
< 0.001) for the association between diabetes and frailty. People who were hospitalized for any cause during the previous year, those receiving both insulin and an oral compound to manage diabetes, and those with peripheral neuropathy showed ORs of 2.32 (95% CI 1.69–3.18,
p
< 0.001), 5.6 (95% CI 1.58–19.8,
p
= 0.008), and 2.02 (95% CI 1.42–2.86,
p
< 0.001), respectively, for being in the most frail group.
Conclusions
People with diabetes have higher frailty scores. Furthermore, older adults with diabetes and higher burden of frailty have more diabetes-related complications.</abstract><cop>Cham</cop><pub>Springer International Publishing</pub><pmid>29181767</pmid><doi>10.1007/s40520-017-0852-2</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0003-4374-976X</orcidid></addata></record> |
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| language | eng |
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| source | SpringerLink Journals - AutoHoldings |
| subjects | Cross-sectional studies Diabetes Frailty Geriatrics/Gerontology Medicine Medicine & Public Health Older people Original Article Peripheral neuropathy |
| title | Frailty, diabetes, and the convergence of chronic disease in an age-related condition: a population-based nationwide cross-sectional analysis of the Mexican nutrition and health survey |
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