Cancer preventive properties of ginger: A brief review
Ginger, the rhizome of Zingiber officinalis, one of the most widely used species of the ginger family, is a common condiment for various foods and beverages. Ginger has a long history of medicinal use dating back 2500 years. Ginger has been traditionally used from time immemorial for varied human ai...
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| Veröffentlicht in: | Food and chemical toxicology 2007-05, Vol.45 (5), p.683-690 |
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| creator | Shukla, Yogeshwer Singh, Madhulika |
| description | Ginger, the rhizome of
Zingiber officinalis, one of the most widely used species of the ginger family, is a common condiment for various foods and beverages. Ginger has a long history of medicinal use dating back 2500 years. Ginger has been traditionally used from time immemorial for varied human ailments in different parts of the globe, to aid digestion and treat stomach upset, diarrhoea, and nausea. Some pungent constituents present in ginger and other zingiberaceous plants have potent antioxidant and anti-inflammatory activities, and some of them exhibit cancer preventive activity in experimental carcinogenesis. The anticancer properties of ginger are attributed to the presence of certain pungent vallinoids, viz. [6]-gingerol and [6]-paradol, as well as some other constituents like shogaols, zingerone etc. A number of mechanisms that may be involved in the chemopreventive effects of ginger and its components have been reported from the laboratory studies in a wide range of experimental models. |
| doi_str_mv | 10.1016/j.fct.2006.11.002 |
| format | Article |
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Zingiber officinalis, one of the most widely used species of the ginger family, is a common condiment for various foods and beverages. Ginger has a long history of medicinal use dating back 2500 years. Ginger has been traditionally used from time immemorial for varied human ailments in different parts of the globe, to aid digestion and treat stomach upset, diarrhoea, and nausea. Some pungent constituents present in ginger and other zingiberaceous plants have potent antioxidant and anti-inflammatory activities, and some of them exhibit cancer preventive activity in experimental carcinogenesis. The anticancer properties of ginger are attributed to the presence of certain pungent vallinoids, viz. [6]-gingerol and [6]-paradol, as well as some other constituents like shogaols, zingerone etc. A number of mechanisms that may be involved in the chemopreventive effects of ginger and its components have been reported from the laboratory studies in a wide range of experimental models.</description><identifier>ISSN: 0278-6915</identifier><identifier>EISSN: 1873-6351</identifier><identifier>DOI: 10.1016/j.fct.2006.11.002</identifier><identifier>PMID: 17175086</identifier><identifier>CODEN: FCTOD7</identifier><language>eng</language><publisher>Oxford: Elsevier Ltd</publisher><subject>6-Gingerol ; 6-Paradol ; Animals ; anticarcinogenic activity ; Anticarcinogenic Agents - chemistry ; Anticarcinogenic Agents - pharmacology ; Anticarcinogenic Agents - therapeutic use ; Biological and medical sciences ; Breast Neoplasms - prevention & control ; Cancer ; Catechols ; Chemoprevention ; Colonic Neoplasms - prevention & control ; condiments ; essential oils ; Fatty Alcohols - chemistry ; Fatty Alcohols - pharmacology ; Gastrointestinal Neoplasms - prevention & control ; Ginger ; ginger root ; Guaiacol - analogs & derivatives ; Guaiacol - chemistry ; Guaiacol - pharmacology ; Humans ; in vitro studies ; in vivo studies ; Ketones - chemistry ; Ketones - pharmacology ; Medical sciences ; medicinal plants ; Oils, Volatile ; Oriental traditional medicine ; plant extracts ; quantitative structure-activity relationships ; rhizomes ; Skin Neoplasms - prevention & control ; Toxicology ; Tumor Cells, Cultured ; Zingiber ; Zingiber officinale ; Zingiber officinale - chemistry</subject><ispartof>Food and chemical toxicology, 2007-05, Vol.45 (5), p.683-690</ispartof><rights>2006 Elsevier Ltd</rights><rights>2007 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c436t-91949421b9cc720f189b4348e2a7ea60bff2a536bb8f09d2b23d05bc01a6117d3</citedby><cites>FETCH-LOGICAL-c436t-91949421b9cc720f189b4348e2a7ea60bff2a536bb8f09d2b23d05bc01a6117d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S027869150600322X$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18692006$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17175086$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shukla, Yogeshwer</creatorcontrib><creatorcontrib>Singh, Madhulika</creatorcontrib><title>Cancer preventive properties of ginger: A brief review</title><title>Food and chemical toxicology</title><addtitle>Food Chem Toxicol</addtitle><description>Ginger, the rhizome of
Zingiber officinalis, one of the most widely used species of the ginger family, is a common condiment for various foods and beverages. Ginger has a long history of medicinal use dating back 2500 years. Ginger has been traditionally used from time immemorial for varied human ailments in different parts of the globe, to aid digestion and treat stomach upset, diarrhoea, and nausea. Some pungent constituents present in ginger and other zingiberaceous plants have potent antioxidant and anti-inflammatory activities, and some of them exhibit cancer preventive activity in experimental carcinogenesis. The anticancer properties of ginger are attributed to the presence of certain pungent vallinoids, viz. [6]-gingerol and [6]-paradol, as well as some other constituents like shogaols, zingerone etc. A number of mechanisms that may be involved in the chemopreventive effects of ginger and its components have been reported from the laboratory studies in a wide range of experimental models.</description><subject>6-Gingerol</subject><subject>6-Paradol</subject><subject>Animals</subject><subject>anticarcinogenic activity</subject><subject>Anticarcinogenic Agents - chemistry</subject><subject>Anticarcinogenic Agents - pharmacology</subject><subject>Anticarcinogenic Agents - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Breast Neoplasms - prevention & control</subject><subject>Cancer</subject><subject>Catechols</subject><subject>Chemoprevention</subject><subject>Colonic Neoplasms - prevention & control</subject><subject>condiments</subject><subject>essential oils</subject><subject>Fatty Alcohols - chemistry</subject><subject>Fatty Alcohols - pharmacology</subject><subject>Gastrointestinal Neoplasms - prevention & control</subject><subject>Ginger</subject><subject>ginger root</subject><subject>Guaiacol - analogs & derivatives</subject><subject>Guaiacol - chemistry</subject><subject>Guaiacol - pharmacology</subject><subject>Humans</subject><subject>in vitro studies</subject><subject>in vivo studies</subject><subject>Ketones - chemistry</subject><subject>Ketones - pharmacology</subject><subject>Medical sciences</subject><subject>medicinal plants</subject><subject>Oils, Volatile</subject><subject>Oriental traditional medicine</subject><subject>plant extracts</subject><subject>quantitative structure-activity relationships</subject><subject>rhizomes</subject><subject>Skin Neoplasms - prevention & control</subject><subject>Toxicology</subject><subject>Tumor Cells, Cultured</subject><subject>Zingiber</subject><subject>Zingiber officinale</subject><subject>Zingiber officinale - chemistry</subject><issn>0278-6915</issn><issn>1873-6351</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kMFuEzEQhi0EomnhAbjAXsptlxl717uGUxVRilSJA_Rs2d5x5CjJBnvTirfvRInUG6eZwzf__PqE-IDQIKD-sm5imBsJoBvEBkC-EgscelVr1eFrsQDZD7U22F2Iy1LWANBjr9-KC-TZwaAXQi_dLlCu9pkeaTenR-J12lOeE5VqitUq7VaUv1Y3lc-JYsVcoqd34k10m0Lvz_NKPNx-_7O8q-9__fi5vLmvQ6v0XBs0rWklehNCLyHiYHyr2oGk68lp8DFK1ynt_RDBjNJLNULnA6DTiP2orsTnUy6X-nugMtttKoE2G7ej6VAsGm0GI3sG8QSGPJWSKdp9TluX_1kEe5Rl15Zl2aMsi2hZFt98PIcf_JbGl4uzHQauz4ArwW1iZlepvHCDNsc85j6duOgm61aZmYffElCx8IGfKya-nQhiWSww2xISsfkxZeJa45T-U_QZ_HCOiQ</recordid><startdate>20070501</startdate><enddate>20070501</enddate><creator>Shukla, Yogeshwer</creator><creator>Singh, Madhulika</creator><general>Elsevier Ltd</general><general>Elsevier Science</general><scope>FBQ</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U7</scope><scope>C1K</scope></search><sort><creationdate>20070501</creationdate><title>Cancer preventive properties of ginger: A brief review</title><author>Shukla, Yogeshwer ; Singh, Madhulika</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c436t-91949421b9cc720f189b4348e2a7ea60bff2a536bb8f09d2b23d05bc01a6117d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>6-Gingerol</topic><topic>6-Paradol</topic><topic>Animals</topic><topic>anticarcinogenic activity</topic><topic>Anticarcinogenic Agents - chemistry</topic><topic>Anticarcinogenic Agents - pharmacology</topic><topic>Anticarcinogenic Agents - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Breast Neoplasms - prevention & control</topic><topic>Cancer</topic><topic>Catechols</topic><topic>Chemoprevention</topic><topic>Colonic Neoplasms - prevention & control</topic><topic>condiments</topic><topic>essential oils</topic><topic>Fatty Alcohols - chemistry</topic><topic>Fatty Alcohols - pharmacology</topic><topic>Gastrointestinal Neoplasms - prevention & control</topic><topic>Ginger</topic><topic>ginger root</topic><topic>Guaiacol - analogs & derivatives</topic><topic>Guaiacol - chemistry</topic><topic>Guaiacol - pharmacology</topic><topic>Humans</topic><topic>in vitro studies</topic><topic>in vivo studies</topic><topic>Ketones - chemistry</topic><topic>Ketones - pharmacology</topic><topic>Medical sciences</topic><topic>medicinal plants</topic><topic>Oils, Volatile</topic><topic>Oriental traditional medicine</topic><topic>plant extracts</topic><topic>quantitative structure-activity relationships</topic><topic>rhizomes</topic><topic>Skin Neoplasms - prevention & control</topic><topic>Toxicology</topic><topic>Tumor Cells, Cultured</topic><topic>Zingiber</topic><topic>Zingiber officinale</topic><topic>Zingiber officinale - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shukla, Yogeshwer</creatorcontrib><creatorcontrib>Singh, Madhulika</creatorcontrib><collection>AGRIS</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Toxicology Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><jtitle>Food and chemical toxicology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shukla, Yogeshwer</au><au>Singh, Madhulika</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cancer preventive properties of ginger: A brief review</atitle><jtitle>Food and chemical toxicology</jtitle><addtitle>Food Chem Toxicol</addtitle><date>2007-05-01</date><risdate>2007</risdate><volume>45</volume><issue>5</issue><spage>683</spage><epage>690</epage><pages>683-690</pages><issn>0278-6915</issn><eissn>1873-6351</eissn><coden>FCTOD7</coden><abstract>Ginger, the rhizome of
Zingiber officinalis, one of the most widely used species of the ginger family, is a common condiment for various foods and beverages. Ginger has a long history of medicinal use dating back 2500 years. Ginger has been traditionally used from time immemorial for varied human ailments in different parts of the globe, to aid digestion and treat stomach upset, diarrhoea, and nausea. Some pungent constituents present in ginger and other zingiberaceous plants have potent antioxidant and anti-inflammatory activities, and some of them exhibit cancer preventive activity in experimental carcinogenesis. The anticancer properties of ginger are attributed to the presence of certain pungent vallinoids, viz. [6]-gingerol and [6]-paradol, as well as some other constituents like shogaols, zingerone etc. A number of mechanisms that may be involved in the chemopreventive effects of ginger and its components have been reported from the laboratory studies in a wide range of experimental models.</abstract><cop>Oxford</cop><cop>New York, NY</cop><pub>Elsevier Ltd</pub><pmid>17175086</pmid><doi>10.1016/j.fct.2006.11.002</doi><tpages>8</tpages></addata></record> |
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| subjects | 6-Gingerol 6-Paradol Animals anticarcinogenic activity Anticarcinogenic Agents - chemistry Anticarcinogenic Agents - pharmacology Anticarcinogenic Agents - therapeutic use Biological and medical sciences Breast Neoplasms - prevention & control Cancer Catechols Chemoprevention Colonic Neoplasms - prevention & control condiments essential oils Fatty Alcohols - chemistry Fatty Alcohols - pharmacology Gastrointestinal Neoplasms - prevention & control Ginger ginger root Guaiacol - analogs & derivatives Guaiacol - chemistry Guaiacol - pharmacology Humans in vitro studies in vivo studies Ketones - chemistry Ketones - pharmacology Medical sciences medicinal plants Oils, Volatile Oriental traditional medicine plant extracts quantitative structure-activity relationships rhizomes Skin Neoplasms - prevention & control Toxicology Tumor Cells, Cultured Zingiber Zingiber officinale Zingiber officinale - chemistry |
| title | Cancer preventive properties of ginger: A brief review |
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