Polymorphisms in the MMP1 and MMP3 promoter and non-small cell lung carcinoma in North China

Matrix metalloproteinases (MMPs) are proteolytic enzymes that regulate various cell behaviors in cancer biology, via their basic function of degradation of proteins. Genetic variations in several MMP promoters may influence transcription and expression of MMPs. The aim of this study is to assess the...

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Veröffentlicht in:	Carcinogenesis (New York) 2005-02, Vol.26 (2), p.481-486
Hauptverfasser:	Fang, Shumei, Jin, Xia, Wang, Rui, Li, Yan, Guo, Wei, Wang, Na, Wang, Yimin, Wen, Denggui, Wei, Lizhen, Zhang, Jianhui
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Alleles Biological and medical sciences Carcinogenesis, carcinogens and anticarcinogens Carcinoma, Non-Small-Cell Lung - genetics Case-Control Studies China confidence interval Female Genetic Predisposition to Disease Humans Lung Neoplasms - genetics Lymphatic Metastasis Male Matrix Metalloproteinase 1 - genetics Matrix Metalloproteinase 3 - genetics matrix metalloproteinases Medical sciences Middle Aged MMPs non-small cell lung carcinoma NSCLC odds ratio Polymorphism, Single Nucleotide - genetics Promoter Regions, Genetic single nucleotide polymorphisms Smoking - adverse effects SNP Tumors
Online-Zugang:	Volltext
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