Phase II study of antineoplaston A10 and AS2-1 in children with recurrent and progressive multicentric glioma : a preliminary report

To evaluate the response rates, survival and toxicity of treatment with antineoplaston A10 and AS2-1 (ANP) in the first 12 children enrolled in our studies diagnosed with incurable recurrent and progressive multicentric glioma. The patients' median age was 9 years. Six patients were diagnosed w...

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Veröffentlicht in:	Drugs in R&D 2004, Vol.5 (6), p.315-326
Hauptverfasser:	Burzynski, Stanislaw R, Weaver, Robert A, Lewy, Robert I, Janicki, Tomasz J, Jurida, Gabor F, Szymkowski, Barbara G, Khan, Mohammad I, Bestak, Marc
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Antineoplastic Agents - adverse effects Antineoplastic Agents - therapeutic use Astrocytoma - drug therapy Astrocytoma - pathology Benzeneacetamides - adverse effects Benzeneacetamides - therapeutic use Brain Neoplasms - drug therapy Child Child, Preschool Disease Progression Drug Combinations Drug Therapy, Combination Female Glioma - drug therapy Glutamine - adverse effects Glutamine - analogs & derivatives Glutamine - therapeutic use Humans Infant Magnetic Resonance Imaging Male Neoplasm Recurrence, Local - prevention & control Phenylacetates - adverse effects Phenylacetates - therapeutic use Piperidones - adverse effects Piperidones - therapeutic use Survival Analysis Treatment Outcome
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