Production of radical species and modification of DNA through one-electron reduction with indium metal

Production of radical species and modification of DNA through one-electron reduction with indium metal

Indium metal produced radical species on DNA through one-electron reduction of 5-iodouracil, and DNA modification via a radical intermediate became possible by the use of an aqueous mixture containing both indium and a radical acceptor.

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Bibliographische Detailangaben
Veröffentlicht in:Tetrahedron letters 2007-04, Vol.48 (18), p.3167-3169
Hauptverfasser: Tanaka, Kazuo, Kamei, Taku, Okamoto, Akimitsu
Format: Artikel
Sprache:eng
Schlagworte:
5-Halouracil
DNA
Indium
One-electron reduction
Radical
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Beschreibung
Zusammenfassung:Indium metal produced radical species on DNA through one-electron reduction of 5-iodouracil, and DNA modification via a radical intermediate became possible by the use of an aqueous mixture containing both indium and a radical acceptor.
ISSN:0040-4039
1873-3581
DOI:10.1016/j.tetlet.2007.03.056