Effect of aroclor 1248 and two pure PCB congeners on phospholipase D activity in rat renal tubular cell cultures

This paper elucidates the effect of different polychlorinated biphenyls (PCBs) on the phospholipase D (PLD) activity in soluble and particulate fractions of rat renal proximal tubular culture cells. Treatment with Aroclor 1248 (a commercial PCB mixture) caused a marked increase in the activity of PL...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of biochemical and molecular toxicology 2007-04, Vol.21 (2), p.68-75
Hauptverfasser:	Santiago, Mercedes Fernández, López-Aparicio, Pilar, Recio, María N., Pérez-Albarsanz, Miguel A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aroclor 1248 Aroclors - pharmacology Cells, Cultured Environmental Pollutants - pharmacology Gene Expression Regulation, Enzymologic - drug effects Kidney Tubules, Proximal - enzymology PCB Congeners Phospholipase D Phospholipase D - biosynthesis PLD1 Polychlorinated Biphenyls Rats Renal Cell Cultures Structure-Activity Relationship
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!