A microbeam study of DNA double-strand breaks in bystander primary human fibroblasts

Radiation-induced bystander effect has been well documented. However, the mechanisms are poorly understood. How we incorporate this effect into the classical models of risk assessment remains an open question. Here, the induction of bystander effect was studied by assessing DNA double-strand break (...

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Veröffentlicht in:	Radiation protection dosimetry 2006-12, Vol.122 (1-4), p.256-259
Hauptverfasser:	Smilenov, L. B., Hall, E. J., Bonner, W. M., Sedelnikova, O. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Alpha Particles Bystander Effect - physiology Bystander Effect - radiation effects Cell Line DNA - genetics DNA - radiation effects DNA Damage Dose-Response Relationship, Radiation Fibroblasts - physiology Fibroblasts - radiation effects Humans Radiation Dosage Radiation Tolerance - physiology Radiation Tolerance - radiation effects
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