Exposure to the Immunosuppresant, Perfluorooctanoic Acid, Enhances the Murine IgE and Airway Hyperreactivity Response to Ovalbumin

These studies were conducted to investigate the role of dermal exposure to perfluorooctanoic acid (PFOA), a known immunosuppressant, on the hypersensitivity response to ovalbumin (OVA) in a murine model of asthma. PFOA has had widespread use as a carpet and fabric protectant. BALB/c mice were expose...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Toxicological sciences 2007-06, Vol.97 (2), p.375-383
Hauptverfasser:	Fairley, Kimberly J., Purdy, Rich, Kearns, Shaun, Anderson, Stacey E., Meade, BJ
Format:	Artikel
Sprache:	eng
Schlagworte:	airway hyperreactivity IgE ovalbumin perfluorooctanoic acid
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!