Microfluidic reactor for lipase-catalyzed regioselective synthesis of neohesperidin ester derivatives and their antimicrobial activity research

Lipase-catalyzed regioselective synthesis of neohesperidin ester derivatives was performed by Lipase TL IM from Thermomyces lanuginosus in a continuous-flow microreactor and then their antimicrobial activity was studied. It appears that neohesperidin, neohesperidin dihydrochalcone with primary OH on...

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Veröffentlicht in:	Carbohydrate research 2018-01, Vol.455, p.32-38
Hauptverfasser:	Du, Lihua, Jiang, Zhipeng, Xu, Liangliang, Zhou, Nani, Shen, Jiahong, Dong, Zhen, Shen, Le, Wang, Hong, Luo, Xiping
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Bacterial Agents - chemical synthesis Anti-Bacterial Agents - chemistry Anti-Bacterial Agents - pharmacology Bioreactors Catalysis Enzymatic synthesis Enzymes, Immobilized - metabolism Gram-Negative Bacteria - drug effects Gram-Positive Bacteria - drug effects Hesperidin - analogs & derivatives Hesperidin - chemical synthesis Hesperidin - chemistry Hesperidin - pharmacology Lipase - metabolism Lipases Microfluidics - methods Microreactor Neohesperidin Regioselectivity Stereoisomerism
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