Tailoring nicotine replacement therapy : Rationale and potential approaches
Nicotine replacement therapy (NRT) is an effective treatment for smoking cessation, but as with all such pharmacotherapies, the majority of smokers who use NRT products do not stop smoking or remain abstinent long term. Treatment outcome is affected by a range of individual-specific factors, as well...
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| Veröffentlicht in: | CNS drugs 2006-01, Vol.20 (4), p.281-291 |
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| creator | MCCLURE, Jennifer B SWAN, Gary E |
| description | Nicotine replacement therapy (NRT) is an effective treatment for smoking cessation, but as with all such pharmacotherapies, the majority of smokers who use NRT products do not stop smoking or remain abstinent long term. Treatment outcome is affected by a range of individual-specific factors, as well as the pharmacokinetic profile of each NRT formulation. This has led to speculation that abstinence rates could be improved if NRT treatments were individually tailored to best match each individual's needs and preferences. There are also populations for whom special product and dosage considerations are warranted to maximise treatment safety.This paper reviews the rationale for NRT treatment, standard dose recommendations and recommendations for how to best match NRT treatment to the specific needs of individual smokers. We also review emerging evidence that genetic profiling may one day be a useful consideration for tailoring NRT treatment. |
| doi_str_mv | 10.2165/00023210-200620040-00002 |
| format | Article |
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| fulltext | fulltext |
| identifier | ISSN: 1172-7047 |
| ispartof | CNS drugs, 2006-01, Vol.20 (4), p.281-291 |
| issn | 1172-7047 1179-1934 |
| language | eng |
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| source | MEDLINE; SpringerLink Journals |
| subjects | Animals Biological and medical sciences Drug Delivery Systems Drug Eruptions Humans Medical sciences Nicotine - administration & dosage Nicotine - standards Nicotinic Agonists - administration & dosage Nicotinic Agonists - standards Smoking Cessation - methods Tobacco Use Disorder - drug therapy Tobacco, tobacco smoking Toxicology |
| title | Tailoring nicotine replacement therapy : Rationale and potential approaches |
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