Galectin-1: A Jack-of-All-Trades in the Resolution of Acute and Chronic Inflammation

Regulatory signals provide negative input to immunological networks promoting resolution of acute and chronic inflammation. Galectin-1 (Gal-1), a member of a family of evolutionarily conserved glycan-binding proteins, displays broad anti-inflammatory and proresolving activities by targeting multiple...

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Veröffentlicht in:	The Journal of immunology (1950) 2017-12, Vol.199 (11), p.3721-3730
Hauptverfasser:	Sundblad, Victoria, Morosi, Luciano G, Geffner, Jorge R, Rabinovich, Gabriel A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Autoimmune diseases Autoimmune Diseases - immunology Cancer Cell Movement Cell survival Chronic Disease Compartments Cytokines Degranulation Female Galectin 1 - immunology Galectin-1 Glycan Humans Hypersensitivity Hypersensitivity - immunology Immunology Immunomodulation Immunoregulation Immunosuppression Infection - immunology Inflammation Inflammation - immunology Leukocyte migration Leukocytes (eosinophilic) Lymphocytes B Lymphocytes T Molecular Targeted Therapy Neoplasms - immunology Pregnancy Pregnancy - immunology Proteins Receptor density
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