A multiphysics approach for modeling early atherosclerosis

This work is devoted to the development of a mathematical model of the early stages of atherosclerosis incorporating processes of all time scales of the disease and to show their interactions. The cardiovascular mechanics is modeled by a fluid–structure interaction approach coupling a non-Newtonian...

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Veröffentlicht in:	Biomechanics and modeling in mechanobiology 2018-06, Vol.17 (3), p.617-644
Hauptverfasser:	Thon, M. P., Hemmler, A., Glinzer, A., Mayr, M., Wildgruber, M., Zernecke-Madsen, A., Gee, M. W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta Arteriosclerosis Atherosclerosis Atherosclerosis - pathology Atherosclerosis - physiopathology Biological and Medical Physics Biomedical Engineering and Bioengineering Biophysics Blood flow Blood Flow Velocity Calibration Computation Computer applications Constitutive equations Constitutive relationships Endothelium Engineering Hemodynamics Humans Lipoproteins Mathematical models Mechanical stimuli Mice, Inbred C57BL Models, Cardiovascular Newtonian fluids Non Newtonian fluids Original Paper Permeability Pressure Pulsatile Flow Reaction-diffusion equations Reproducibility of Results Rheology Shear stress Space life sciences Theoretical and Applied Mechanics
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