Very mild disease phenotype of congenic Cftr super()TgH(neoim)Hgu ystic fibrosis mice

Background A major boost to cystic fibrosis disease research was given by the generation of various mouse models using gene targeting in embryonal stem cells. Moreover, the introduction of the same mutation on different inbred strains generating congenic strains facilitated the search for modifier g...

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Veröffentlicht in:BMC genetics 2008-01, Vol.9, p.28-28
Hauptverfasser: Toth, Balazs, Wilke, Martina, Stanke, Frauke, Dorsch, Martina, Jansen, Silke, Wedekind, Dirk, Charizopoulou, Nikoletta, Bot, Alice, Burmester, Marion, Leonhard-Marek, Sabine, de Jonge, Hugo R, Hedrich, Hans-Juergen, Breves, Gerhard, Tuemmler, Burkhard
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Sprache:eng
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