Practical prognostic score for predicting the extent of resection and neurological outcome of gliomas in the sensorimotor area

•Resecting gliomas in highly functional areas aims to achieve large resection while maintaining optimal functional status.•We constructed a prognostic score for predicting functional outcome and extent of resection in sensorimotor area tumors.•The score demonstrated a very good power in discerning good and bad outcomes for functional outcome and EOR.•We hypothesize that this index could help in choosing the most appropriate strategy for this class of patient. In this prospective study, we assessed the utility of a novel prognostic score (PS) in guiding the surgical strategy of patients with sensorimotor area gliomas. Form December 2012 to April 2016, we collected data from patients diagnosed with brain gliomas in the sensorimotor area. All the patients had intraoperatively confirmed contiguity or continuity with sensorimotor cortical and subcortical structures. Several clinical and radiological factors were analyzed to generate a PS for each patient (range 1–8). The end-points included the extent of resection (EOR) and neurological outcome (modified Rankin Score; mRS). We assessed the predictive power of the PS using different analyses. Crosstabs analyses and Fisher’s exact test (Fet) were used to evaluate the possible predictive parameters, and for the classification of positive or negative outcomes for the chosen proxies; the significance threshold was set at p