Oxidative stress-induced inflammatory responses and effects of N-acetylcysteine in bovine mammary alveolar cells

Bovine mastitis, an inflammation of the udder, results in reduced milk production and poor milk quality. Mastitis is usually, but not always, a response to pathogen infection. High milk yield can produce oxidative stress in the mammary tissue. High milk yield is also known to be associated with bovi...

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Veröffentlicht in:	Journal of dairy research 2017-11, Vol.84 (4), p.418-425
Hauptverfasser:	Bae, Hyojin, Jeong, Chang Hee, Cheng, Wei Nee, Hong, Kwonho, Seo, Han Geuk, Han, Sung Gu
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcysteine Acetylcysteine - administration & dosage Activation AKT protein Alveoli Animal lactation Animals Antioxidants Attenuation Biology Biomarkers Biotechnology Carbon monoxide Cattle Cells, Cultured Chronic obstructive pulmonary disease Cyclooxygenase 2 - analysis Cyclooxygenase-2 Dairy cattle Dairy industry Disease Epithelial Cells - drug effects Epithelial Cells - physiology Extracellular signal-regulated kinase Female Glutathione Humans Immunology Inflammation Inflammation - etiology Intracellular Intracellular signalling Mammary Glands, Animal - cytology MAP Kinase Signaling System - drug effects MAP Kinase Signaling System - physiology Mastitis Mastitis, Bovine - etiology Mastitis, Bovine - prevention & control Menadione Milk Milk production NF-kappa B - antagonists & inhibitors NF-kappa B - physiology NF-κB protein Oxidative stress Oxidative Stress - physiology Pathogens Penicillin Pharmacology Physiology Pretreatment Proto-Oncogene Proteins c-akt - antagonists & inhibitors Proto-Oncogene Proteins c-akt - physiology Reactive oxygen species Reactive Oxygen Species - pharmacology Rodents Signal transduction Studies Superoxide Udder Vitamin K 3 - pharmacology
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