An Essential Role for TNF in Modulating Thresholds for Survival, Activation, and Tolerance of CD8 super(+) T Cells

TNF and its receptors p55 and p75 are known to be important in the homeostasis of the peripheral immune system. Previous studies have presented apparently contradictory evidence for an in vivo role of TNF in T cells. In this study, we analyzed TNF-deficient mice crossed with the F5 TCR-transgenic an...

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Veröffentlicht in:Journal of Immunology 2007-06, Vol.178 (11), p.6735-6745
Hauptverfasser: Chatzidakis, Ioannis, Fousteri, Georgia, Tsoukatou, Debbie, Kollias, George, Mamalaki, Clio
Format: Artikel
Sprache:eng
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