Stress hormones concentrations in the normal microenvironment predict risk for chemically induced cancer in rats

•Stress hormones levels in the microenvironment predicted carcinogenesis in rats.•Norepinephrine and corticosterone predicted differently chemical carcinogenesis.•Brain-derived neurotrophic factor is a promising mediator for oral carcinogenesis.•Individual endocrine differences can modulate cancer d...

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Veröffentlicht in:	Psychoneuroendocrinology 2018-03, Vol.89, p.229-238
Hauptverfasser:	Valente, Vitor Bonetti, Verza, Flávia Alves, Lopes, Felipe Yudi Kabeya, Ferreira, Joana Zafalon, dos Santos, Paulo Sérgio Patto, Sundefeld, Maria Lúcia Marçal Mazza, Biasoli, Éder Ricardo, Miyahara, Glauco Issamu, Soubhia, Ana Maria Pires, de Andrade, Mariza, de Oliveira, Sandra Helena Penha, Bernabé, Daniel Galera
Format:	Artikel
Sprache:	eng
Schlagworte:	4-Nitroquinoline-1-oxide - pharmacology Adrenocorticotropic Hormone Animals BDNF Biomarkers, Tumor Brain-Derived Neurotrophic Factor Cancer Carcinogenesis Carcinogenesis - metabolism Carcinogens Cellular Microenvironment - physiology Corticosterone Disease Models, Animal Hormones - metabolism Male Neoplasms - chemically induced Neoplasms - metabolism Norepinephrine Oral cancer Rats Rats, Wistar Risk Factors Stress hormones Tongue - metabolism Tongue Neoplasms - chemically induced Tongue Neoplasms - metabolism
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