The Micro-Ribonucleic Acid (miRNA) miR-206 Targets the Human Estrogen Receptor-α (ERα) and Represses ERα Messenger RNA and Protein Expression in Breast Cancer Cell Lines

Micro-RNAs are small noncoding RNAs, which diminish the stability and/or translation of mRNAs. This study examined whether miR-206, previously shown to be elevated in estrogen receptor (ER)α-negative breast cancer, regulates the expression of ERα. Two putative miR-206 sites, (hERα1 and hERα2), were...

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Veröffentlicht in:Molecular endocrinology (Baltimore, Md.) Md.), 2007-05, Vol.21 (5), p.1132-1147
Hauptverfasser: Adams, Brian D, Furneaux, Henry, White, Bruce A
Format: Artikel
Sprache:eng
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