RGK Small GTP-binding Proteins Interact with the Nucleotide Kinase Domain of Ca super(2+)-channel beta -Subunits via an Uncommon Effector Binding Domain
RGK proteins (Kir/Gem, Rad, Rem, and Rem2) form a small subfamily of the Ras superfamily. Despite a conserved GTP binding core domain, several differences suggest that structure, mechanism of action, and functional regulation differ from Ras. RGK proteins down-regulate voltage-gated calcium channel...
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Veröffentlicht in: | The Journal of biological chemistry 2007-04, Vol.282 (15), p.11509-11520 |
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Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Online-Zugang: | Volltext |
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