RGK Small GTP-binding Proteins Interact with the Nucleotide Kinase Domain of Ca super(2+)-channel beta -Subunits via an Uncommon Effector Binding Domain

RGK proteins (Kir/Gem, Rad, Rem, and Rem2) form a small subfamily of the Ras superfamily. Despite a conserved GTP binding core domain, several differences suggest that structure, mechanism of action, and functional regulation differ from Ras. RGK proteins down-regulate voltage-gated calcium channel...

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Veröffentlicht in:The Journal of biological chemistry 2007-04, Vol.282 (15), p.11509-11520
Hauptverfasser: Beguin, Pascal, Ng, Yu Jin Alvin, Krause, Carola, Mahalakshmi, Ramasubbu N, Ng, Mei Yong, Hunziker, Walter
Format: Artikel
Sprache:eng
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