Antimicrobial screening of N-[(2-substituted phenyl)-4-oxo-1,3-thiazolidine-3-Yl]isonicotinamides

Antimicrobial screening of N-[(2-substituted phenyl)-4-oxo-1,3-thiazolidine-3-Yl]isonicotinamides

Some new N-[(2-substituted phenyl)-4-oxo-1, 3-thiazolidine-3-yl]isonicotinamide derivatives (3a-e) have been synthesized by the reaction of N'-[(1E)-arylmethylene]isonicotinohydrazide (2a-e) with thioglycolicacid These compounds were characterized on the basis of elemental and spectral analysis...

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Veröffentlicht in:Rasāyan journal of chemistry 2008-06, Vol.1 (2), p.207-211
Hauptverfasser: Bhaskar, V H, Kumar, M, Sangameswaran, B
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Kumar, M
Sangameswaran, B
description Some new N-[(2-substituted phenyl)-4-oxo-1, 3-thiazolidine-3-yl]isonicotinamide derivatives (3a-e) have been synthesized by the reaction of N'-[(1E)-arylmethylene]isonicotinohydrazide (2a-e) with thioglycolicacid These compounds were characterized on the basis of elemental and spectral analysis. The title compounds were screened for their antimicrobial activity and found to exhibit a variable degree of activity.
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title Antimicrobial screening of N-[(2-substituted phenyl)-4-oxo-1,3-thiazolidine-3-Yl]isonicotinamides
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