Immunotherapy of Hepatocellular Carcinoma: Facts and Hopes

Treatment of patients with hepatocellular carcinoma (HCC) in the advanced stage remains a great challenge, with very few drugs approved. After decades of failure of immune therapies, immune checkpoint inhibitors have emerged as potentially effective treatments for patients with HCC in the advanced s...

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Veröffentlicht in:	Clinical cancer research 2018-04, Vol.24 (7), p.1518-1524
Hauptverfasser:	Iñarrairaegui, Mercedes, Melero, Ignacio, Sangro, Bruno
Format:	Artikel
Sprache:	eng
Schlagworte:	Anticancer properties Antitumor activity Apoptosis Biomarkers Cancer Cell death Clinical trials CTLA-4 protein Cytotoxicity Hepatocellular carcinoma Immune checkpoint Immune checkpoint inhibitors Immune system Immunosuppressive agents Immunotherapy Inhibitors Liver cancer Lymphocytes T Monoclonal antibodies Patients PD-1 protein Proteins Synergistic effect Targeted cancer therapy Tumors
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