Expression of Interleukin-11 Receptor in CD38-positive Cells from Patients with Multiple Myeloma

Interleukin-11, a cytokine with multiple biological activities, has been shown to stimulate the proliferation and to support the long-term growth of human myeloma cell lines. Despite this, no expression of the interleukin-11α receptor has so far been demonstrated in myeloma cells. We have investigat...

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Veröffentlicht in:	Leukemia & lymphoma 2004-11, Vol.45 (11), p.2315-2319
Hauptverfasser:	Tsimanis, Alexander, Shtalrid, Mordehai, Shvidel, Lev, Kalinkovich, Alexander, Berrebi, Alain, Klepfish, Abraham
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase - biosynthesis ADP-ribosyl Cyclase 1 Adult Aged Aged, 80 and over Antigens, CD - biosynthesis Bone Marrow Cells - metabolism Cell Proliferation Expression Female Flow Cytometry Humans Interleukin-11 Interleukin-11 Receptor alpha Subunit Interleukin-11α Leukocytes, Mononuclear - metabolism Male Membrane Glycoproteins Middle Aged Multiple Myeloma Multiple Myeloma - metabolism Plasma Cells - metabolism Receptor Receptors, Interleukin - biosynthesis Receptors, Interleukin-11 Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - metabolism Time Factors
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