Increased hippocampal tail volume predicts depression status and remission to anti-depressant medications in major depression

Studies of patients with major depressive disorder (MDD) have consistently reported reduced hippocampal volumes; however, the exact pattern of these volume changes in specific anatomical subfields and their functional significance is unclear. We sought to clarify the relationship between hippocampal...

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Veröffentlicht in:	Molecular psychiatry 2018-08, Vol.23 (8), p.1737-1744
Hauptverfasser:	Maller, J J, Broadhouse, K, Rush, A J, Gordon, E, Koslow, S, Grieve, S M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Age Factors Antidepressive Agents - therapeutic use Behavioral Sciences Biological Psychology Brain Citalopram Citalopram - therapeutic use Cohort Studies Delayed-Action Preparations Depressive Disorder, Major - diagnostic imaging Depressive Disorder, Major - drug therapy Depressive Disorder, Major - pathology Depressive Disorder, Treatment-Resistant - diagnostic imaging Depressive Disorder, Treatment-Resistant - drug therapy Depressive Disorder, Treatment-Resistant - pathology Female Hippocampus Hippocampus - diagnostic imaging Hippocampus - drug effects Hippocampus - pathology Humans Image Interpretation, Computer-Assisted Magnetic Resonance Imaging Male Medicine Medicine & Public Health Mental depression Neuroimaging Neurosciences NMR Nuclear magnetic resonance Organ Size Pattern Recognition, Automated Pharmacotherapy Prognosis Psychiatric Status Rating Scales Psychiatry Remission Remission Induction Sertraline Sertraline - therapeutic use Tails Venlafaxine Venlafaxine Hydrochloride - therapeutic use
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