Staged development of long-lived T-cell receptor αβ TH17 resident memory T-cell population to Candida albicans after skin infection

Candida albicans is a dimorphic fungus to which human subjects are exposed early in life, and by adulthood, it is part of the mycobiome of skin and other tissues. Neonatal skin lacks resident memory T (TRM) cells, but in adults the C albicans skin test is a surrogate for immunocompetence. Young adul...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of allergy and clinical immunology 2018-08, Vol.142 (2), p.647-662
Hauptverfasser:	Park, Chang Ook, Fu, Xiujun, Jiang, Xiaodong, Pan, Youdong, Teague, Jessica E., Collins, Nicholas, Tian, Tian, O'Malley, John T., Emerson, Ryan O., Kim, Ji Hye, Jung, Yookyung, Watanabe, Rei, Fuhlbrigge, Robert C., Carbone, Francis R., Gebhardt, Thomas, Clark, Rachael A., Lin, Charles P., Kupper, Thomas S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Candida albicans CD4+ TRM IL-17 Resident memory T cells TH17 TRM
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!