A biodegradable scaffold enhances differentiation of embryonic stem cells into a thick sheet of retinal cells

Retinal degeneration is a leading cause of blindness in developed countries. Stem cells can be differentiated into retinal organoids to study mechanisms of retinal degeneration, develop therapeutic agents, and potentially serve as replacement tissues. The spherical nature of these retinoids limits t...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biomaterials 2018-02, Vol.154, p.158-168
Hauptverfasser:	Singh, Deepti, Wang, Shao-Bin, Xia, Tina, Tainsh, Laurel, Ghiassi-Nejad, Maryam, Xu, Tao, Peng, Shaomin, Adelman, Ron A., Rizzolo, Lawrence J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biodegradable scaffold Human embryonic stem cells Human induced pluripotent stem cells Retinal degeneration Retinal differentiation Retinoids Tissue replacement therapy
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!