APOBEC3B edits HBV DNA and inhibits HBV replication during reverse transcription

Hepatitis B virus is a partially double-stranded DNA virus that replicates by reverse transcription, which occurs within viral core particles in the cytoplasm. The cytidine deaminase APOBEC3B is a cellular restriction factor for HBV. Recently, it was reported that APOBEC3B can edit HBV cccDNA in the...

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Veröffentlicht in:	Antiviral research 2018-01, Vol.149, p.16-25
Hauptverfasser:	Chen, Yanmeng, Hu, Jie, Cai, Xuefei, Huang, Yao, Zhou, Xing, Tu, Zeng, Hu, Jieli, Tavis, John E., Tang, Ni, Huang, Ailong, Hu, Yuan
Format:	Artikel
Sprache:	eng
Schlagworte:	APOBEC3B Deaminase Hepatitis B virus Inhibition
Online-Zugang:	Volltext
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