Proteoglycans remodeling in cancer: Underlying molecular mechanisms

Extracellular matrix is a highly dynamic macromolecular network. Proteoglycans are major components of extracellular matrix playing key roles in its structural organization and cell signaling contributing to the control of numerous normal and pathological processes. As multifunctional molecules, pro...

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Veröffentlicht in:	Matrix biology 2019-01, Vol.75-76, p.220-259
Hauptverfasser:	Theocharis, Achilleas D., Karamanos, Nikos K.
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Cancer Cell surface Decorin Drug resistance Extracellular matrix Glycosaminoglycans Glypicans Macromolecules Malignancy Molecular modelling Morphogenesis Perlecan Phenotypes Proteoglycans Receptor mechanisms Serglycin Stroma Syndecans Tumorigenesis Versican Wound healing
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