miR‐140‐5p‐mediated regulation of the proliferation and differentiation of human dental pulp stem cells occurs through the lipopolysaccharide/toll‐like receptor 4 signaling pathway

Human dental pulp stem cells (DPSCs) are oral mesenchymal stem cells with potential to differentiate into various cell types. Recent studies of DPSCs have focused on microRNAs (miRNAs), a class of small noncoding RNAs that play crucial roles in regulating DPSC phenotypes. In the current study, the e...

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Veröffentlicht in:	European journal of oral sciences 2017-12, Vol.125 (6), p.419-425
Hauptverfasser:	Sun, De‐gang, Xin, Bing‐chang, Wu, Di, Zhou, Lei, Wu, Hong‐bin, Gong, Wen, Lv, Jian
Format:	Artikel
Sprache:	eng
Schlagworte:	3' Untranslated regions Apoptosis Blotting, Western Cell Cycle Cell Differentiation - genetics Cell proliferation Cell Proliferation - genetics Cell Survival Cells, Cultured Dental pulp Dental Pulp - cytology Dentistry Differentiation Humans Immune system In Vitro Techniques Inhibitors lipopolysaccharide Lipopolysaccharides Mesenchymal Stromal Cells - metabolism Mesenchyme microRNA, oral mesenchymal stem cells MicroRNAs - genetics miRNA Odontoblasts - metabolism Phenotype Proteins Reverse Transcriptase Polymerase Chain Reaction Signal transduction Signal Transduction - genetics Signaling small noncoding RNAs Stem cells TLR4 protein Toll-Like Receptor 4 - genetics Toll-like receptors
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