Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis

Phytochemical investigation of the alkaloid extract of Palicourea sessilis by LC-HRMS/MS using molecular networking and an in silico MS/MS fragmentation approach suggested the presence of several new monoterpene indole alkaloids. These compounds were isolated by semipreparative HPLC, and their struc...

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Veröffentlicht in:	Journal of natural products (Washington, D.C.) D.C.), 2017-11, Vol.80 (11), p.3032-3037
Hauptverfasser:	Klein-Júnior, Luiz C, Cretton, Sylvian, Allard, Pierre-Marie, Genta-Jouve, Grégory, Passos, Carolina S, Salton, Juliana, Bertelli, Pablo, Pupier, Marion, Jeannerat, Damien, Heyden, Yvan Vander, Gasper, André L, Wolfender, Jean-Luc, Christen, Philippe, Henriques, Amélia T
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholinesterase - drug effects Brazil Cholinesterase Inhibitors - chemistry Cholinesterase Inhibitors - isolation & purification Cholinesterase Inhibitors - pharmacology Molecular Structure Nuclear Magnetic Resonance, Biomolecular Plant Leaves - chemistry Rubiaceae - chemistry Secologanin Tryptamine Alkaloids - chemistry Secologanin Tryptamine Alkaloids - isolation & purification Tryptamines - chemistry
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