Is it really possible to predict the consistency of a pituitary adenoma preoperatively?
To determine if the consistency of pituitary adenomas can be predicted based on a preoperative MRI study and to assess the surgical outcome of firm pituitary adenomas. One hundred consecutive patients with pituitary adenomas and suprasellar extension were operated by a transsphenoidal approach from...
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| Veröffentlicht in: | Neuro-chirurgie 2017-12, Vol.63 (6), p.453-457 |
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| creator | Thotakura, A.K. Patibandla, M.R. Panigrahi, M.K. Mahadevan, A. |
| description | To determine if the consistency of pituitary adenomas can be predicted based on a preoperative MRI study and to assess the surgical outcome of firm pituitary adenomas.
One hundred consecutive patients with pituitary adenomas and suprasellar extension were operated by a transsphenoidal approach from July 2003 to December 2006. In addition to the neurological examination, the patients were evaluated by ophthalmological, endocrinological and radiological workups. The signal intensity of the lesion on T2WI and other dimensions of the tumors were included in the MRI study.
There were 52 male and 48 female patients with a mean age of 42.47 years. The mean diameter of the tumor was 32.97mm and the mean SSE was 14.95mm. Six out of 100 patients had firm adenomas peroperatively. Only one of the six patients had isointense SI on T2 WI. Of these 6 patients, total excision was performed in 1 patient, subtotal in 3 patients and partial excision in 2 patients. Among the six patients with firm adenomas, 4 had preoperative hypopituitarism (P |
| doi_str_mv | 10.1016/j.neuchi.2017.06.003 |
| format | Article |
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One hundred consecutive patients with pituitary adenomas and suprasellar extension were operated by a transsphenoidal approach from July 2003 to December 2006. In addition to the neurological examination, the patients were evaluated by ophthalmological, endocrinological and radiological workups. The signal intensity of the lesion on T2WI and other dimensions of the tumors were included in the MRI study.
There were 52 male and 48 female patients with a mean age of 42.47 years. The mean diameter of the tumor was 32.97mm and the mean SSE was 14.95mm. Six out of 100 patients had firm adenomas peroperatively. Only one of the six patients had isointense SI on T2 WI. Of these 6 patients, total excision was performed in 1 patient, subtotal in 3 patients and partial excision in 2 patients. Among the six patients with firm adenomas, 4 had preoperative hypopituitarism (P<0.001). There was a statistically significant correlation between consistency and the postoperative permanent hypopituitarism (P<0.001). The average follow up was 43.5 months. The literature is reviewed and various aspects of pituitary adenoma consistency are discussed.
With the present study, the consistency of pituitary adenomas cannot be reliably predicted based on a preoperative MRI study. Patients with firm adenomas likely to have more incidence of preoperative hypopituitarism and postoperative permanent hypopituitarism.</description><identifier>ISSN: 0028-3770</identifier><identifier>EISSN: 1773-0619</identifier><identifier>DOI: 10.1016/j.neuchi.2017.06.003</identifier><identifier>PMID: 29122303</identifier><language>eng</language><publisher>France: Elsevier Masson SAS</publisher><subject>Adenoma - diagnostic imaging ; Adenoma - pathology ; Adenoma - surgery ; Adult ; Consistency ; Curettage ; Female ; Fibrous adenoma ; Firm adenoma ; Humans ; Hypophysectomy - adverse effects ; Hypophysectomy - methods ; Hypopituitarism - etiology ; Magnetic Resonance Imaging ; Male ; Pituitary adenoma ; Pituitary Neoplasms - diagnostic imaging ; Pituitary Neoplasms - pathology ; Pituitary Neoplasms - surgery ; Vacuum Curettage</subject><ispartof>Neuro-chirurgie, 2017-12, Vol.63 (6), p.453-457</ispartof><rights>2017 Elsevier Masson SAS</rights><rights>Copyright © 2017 Elsevier Masson SAS. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c362t-57872756c09d47c0bee9e8677db53988c91354057005c8c36171f56c3174aca73</citedby><cites>FETCH-LOGICAL-c362t-57872756c09d47c0bee9e8677db53988c91354057005c8c36171f56c3174aca73</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.sciencedirect.com/science/article/pii/S0028377017301133$$EHTML$$P50$$Gelsevier$$H</linktohtml><link.rule.ids>314,776,780,3537,27901,27902,65306</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29122303$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Thotakura, A.K.</creatorcontrib><creatorcontrib>Patibandla, M.R.</creatorcontrib><creatorcontrib>Panigrahi, M.K.</creatorcontrib><creatorcontrib>Mahadevan, A.</creatorcontrib><title>Is it really possible to predict the consistency of a pituitary adenoma preoperatively?</title><title>Neuro-chirurgie</title><addtitle>Neurochirurgie</addtitle><description>To determine if the consistency of pituitary adenomas can be predicted based on a preoperative MRI study and to assess the surgical outcome of firm pituitary adenomas.
One hundred consecutive patients with pituitary adenomas and suprasellar extension were operated by a transsphenoidal approach from July 2003 to December 2006. In addition to the neurological examination, the patients were evaluated by ophthalmological, endocrinological and radiological workups. The signal intensity of the lesion on T2WI and other dimensions of the tumors were included in the MRI study.
There were 52 male and 48 female patients with a mean age of 42.47 years. The mean diameter of the tumor was 32.97mm and the mean SSE was 14.95mm. Six out of 100 patients had firm adenomas peroperatively. Only one of the six patients had isointense SI on T2 WI. Of these 6 patients, total excision was performed in 1 patient, subtotal in 3 patients and partial excision in 2 patients. Among the six patients with firm adenomas, 4 had preoperative hypopituitarism (P<0.001). There was a statistically significant correlation between consistency and the postoperative permanent hypopituitarism (P<0.001). The average follow up was 43.5 months. The literature is reviewed and various aspects of pituitary adenoma consistency are discussed.
With the present study, the consistency of pituitary adenomas cannot be reliably predicted based on a preoperative MRI study. Patients with firm adenomas likely to have more incidence of preoperative hypopituitarism and postoperative permanent hypopituitarism.</description><subject>Adenoma - diagnostic imaging</subject><subject>Adenoma - pathology</subject><subject>Adenoma - surgery</subject><subject>Adult</subject><subject>Consistency</subject><subject>Curettage</subject><subject>Female</subject><subject>Fibrous adenoma</subject><subject>Firm adenoma</subject><subject>Humans</subject><subject>Hypophysectomy - adverse effects</subject><subject>Hypophysectomy - methods</subject><subject>Hypopituitarism - etiology</subject><subject>Magnetic Resonance Imaging</subject><subject>Male</subject><subject>Pituitary adenoma</subject><subject>Pituitary Neoplasms - diagnostic imaging</subject><subject>Pituitary Neoplasms - pathology</subject><subject>Pituitary Neoplasms - surgery</subject><subject>Vacuum Curettage</subject><issn>0028-3770</issn><issn>1773-0619</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2017</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kE1LAzEQhoMoWj_-gUiOXnadJN1k96JI8aMgeFE8hjQ7pSnbzZpkhf57U6oePQ0DzzvD-xByyaBkwOTNuuxxtCtXcmCqBFkCiAMyYUqJAiRrDskEgNeFUApOyGmM67yySsIxOeEN41yAmJCPeaQu0YCm67Z08DG6RYc0eToEbJ1NNK2QWt9HFxP2dkv9kho6uDS6ZMKWmhZ7vzE73A8YTHJf2G3vzsnR0nQRL37mGXl_fHibPRcvr0_z2f1LYYXkqahUrbiqpIWmnSoLC8QGa6lUu6hEU9e2YaKaQqUAKlvnDFNsmXHB1NRYo8QZud7fHYL_HDEmvXHRYteZHv0YNWuk4IrVgmd0ukdtyDUDLvUQ3CZ30Az0Tqle671SvVOqQeqsNMeufj6Miw22f6Ffhxm43QOYe345DDpal1VlfQFt0q13_3_4BsKJiNc</recordid><startdate>201712</startdate><enddate>201712</enddate><creator>Thotakura, A.K.</creator><creator>Patibandla, M.R.</creator><creator>Panigrahi, M.K.</creator><creator>Mahadevan, A.</creator><general>Elsevier Masson SAS</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>201712</creationdate><title>Is it really possible to predict the consistency of a pituitary adenoma preoperatively?</title><author>Thotakura, A.K. ; Patibandla, M.R. ; Panigrahi, M.K. ; Mahadevan, A.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c362t-57872756c09d47c0bee9e8677db53988c91354057005c8c36171f56c3174aca73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2017</creationdate><topic>Adenoma - diagnostic imaging</topic><topic>Adenoma - pathology</topic><topic>Adenoma - surgery</topic><topic>Adult</topic><topic>Consistency</topic><topic>Curettage</topic><topic>Female</topic><topic>Fibrous adenoma</topic><topic>Firm adenoma</topic><topic>Humans</topic><topic>Hypophysectomy - adverse effects</topic><topic>Hypophysectomy - methods</topic><topic>Hypopituitarism - etiology</topic><topic>Magnetic Resonance Imaging</topic><topic>Male</topic><topic>Pituitary adenoma</topic><topic>Pituitary Neoplasms - diagnostic imaging</topic><topic>Pituitary Neoplasms - pathology</topic><topic>Pituitary Neoplasms - surgery</topic><topic>Vacuum Curettage</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Thotakura, A.K.</creatorcontrib><creatorcontrib>Patibandla, M.R.</creatorcontrib><creatorcontrib>Panigrahi, M.K.</creatorcontrib><creatorcontrib>Mahadevan, A.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neuro-chirurgie</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Thotakura, A.K.</au><au>Patibandla, M.R.</au><au>Panigrahi, M.K.</au><au>Mahadevan, A.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Is it really possible to predict the consistency of a pituitary adenoma preoperatively?</atitle><jtitle>Neuro-chirurgie</jtitle><addtitle>Neurochirurgie</addtitle><date>2017-12</date><risdate>2017</risdate><volume>63</volume><issue>6</issue><spage>453</spage><epage>457</epage><pages>453-457</pages><issn>0028-3770</issn><eissn>1773-0619</eissn><abstract>To determine if the consistency of pituitary adenomas can be predicted based on a preoperative MRI study and to assess the surgical outcome of firm pituitary adenomas.
One hundred consecutive patients with pituitary adenomas and suprasellar extension were operated by a transsphenoidal approach from July 2003 to December 2006. In addition to the neurological examination, the patients were evaluated by ophthalmological, endocrinological and radiological workups. The signal intensity of the lesion on T2WI and other dimensions of the tumors were included in the MRI study.
There were 52 male and 48 female patients with a mean age of 42.47 years. The mean diameter of the tumor was 32.97mm and the mean SSE was 14.95mm. Six out of 100 patients had firm adenomas peroperatively. Only one of the six patients had isointense SI on T2 WI. Of these 6 patients, total excision was performed in 1 patient, subtotal in 3 patients and partial excision in 2 patients. Among the six patients with firm adenomas, 4 had preoperative hypopituitarism (P<0.001). There was a statistically significant correlation between consistency and the postoperative permanent hypopituitarism (P<0.001). The average follow up was 43.5 months. The literature is reviewed and various aspects of pituitary adenoma consistency are discussed.
With the present study, the consistency of pituitary adenomas cannot be reliably predicted based on a preoperative MRI study. Patients with firm adenomas likely to have more incidence of preoperative hypopituitarism and postoperative permanent hypopituitarism.</abstract><cop>France</cop><pub>Elsevier Masson SAS</pub><pmid>29122303</pmid><doi>10.1016/j.neuchi.2017.06.003</doi><tpages>5</tpages></addata></record> |
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| source | MEDLINE; Elsevier ScienceDirect Journals |
| subjects | Adenoma - diagnostic imaging Adenoma - pathology Adenoma - surgery Adult Consistency Curettage Female Fibrous adenoma Firm adenoma Humans Hypophysectomy - adverse effects Hypophysectomy - methods Hypopituitarism - etiology Magnetic Resonance Imaging Male Pituitary adenoma Pituitary Neoplasms - diagnostic imaging Pituitary Neoplasms - pathology Pituitary Neoplasms - surgery Vacuum Curettage |
| title | Is it really possible to predict the consistency of a pituitary adenoma preoperatively? |
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