Fabrication of flexible thin polyurethane membrane for tissue engineering applications

Thin and flexible polymeric membranes play a critical role in tissue engineering applications for example organs-on-a-chip. These flexible membranes can enable mechanical stretch of the engineered tissue to mimic organ-specific biophysical features, such as breathing. In this work, we report the fab...

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Veröffentlicht in:	Biomedical microdevices 2017-12, Vol.19 (4), p.98-9, Article 98
Hauptverfasser:	Arefin, A., Huang, J-H., Platts, D., Hypes, V. D., Harris, J. F., Iyer, R., Nath, P.
Format:	Artikel
Sprache:	eng
Schlagworte:	A549 Cells Alveoli Biocompatibility Biocompatible Materials - chemistry Biological and Medical Physics Biomedical Engineering and Bioengineering Biomimetic Materials Biophysics Breathing Cell culture Cell Survival Elastic properties Engineering Engineering Fluid Dynamics Fabrication Humans Lab-On-A-Chip Devices Mechanical failure Membranes Membranes - chemistry Models, Theoretical Nanotechnology Optical properties Organs Polymers - chemistry Polyurethane Polyurethane resins Polyurethanes - chemistry Silicon substrates Spin coating Substrates Tissue culture Tissue Engineering Tissue Scaffolds
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Beschreibung
Zusammenfassung:	Thin and flexible polymeric membranes play a critical role in tissue engineering applications for example organs-on-a-chip. These flexible membranes can enable mechanical stretch of the engineered tissue to mimic organ-specific biophysical features, such as breathing. In this work, we report the fabrication of thin (
ISSN:	1387-2176 1572-8781
DOI:	10.1007/s10544-017-0236-6