Radioligands for positron emission tomography imaging of cannabinoid type 2 receptor

The cannabinoid type 2 (CB2) receptor is an immunomodulatory receptor mainly expressed in peripheral cells and organs of the immune system. The expression level of CB2 in the central nervous system under physiological conditions is negligible, however under neuroinflammatory conditions an upregulati...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of labelled compounds & radiopharmaceuticals 2018-03, Vol.61 (3), p.299-308
Hauptverfasser:	Spinelli, Francesco, Mu, Linjing, Ametamey, Simon M.
Format:	Artikel
Sprache:	eng
Schlagworte:	activated microglia Animals Cannabinoids CB2 radioligand Central nervous system Humans Immune system Immunomodulation Inflammatory diseases Medical imaging Microglial cells mRNA neurodegenerative disease neuroinflammation Neuroprotection Organs PET imaging Positron emission Positron emission tomography Positron-Emission Tomography - methods Protein Binding Radioisotopes Radiopharmaceuticals - chemistry Radiopharmaceuticals - pharmacology Receptor, Cannabinoid, CB2 - agonists Receptor, Cannabinoid, CB2 - metabolism Tomography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!