Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort
To examine the prevalence of micro- and macrovascular complications and their associated clinical characteristics at time of type 2 diabetes (T2D) diagnosis. We examined the prevalence of complications and associated clinical characteristics among 6958 newly diagnosed T2D patients enrolled in the pr...
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| Veröffentlicht in: | Journal of diabetes and its complications 2018-01, Vol.32 (1), p.34-40 |
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| creator | Gedebjerg, Anne Almdal, Thomas Peter Berencsi, Klara Rungby, Jørgen Nielsen, Jens Steen Witte, Daniel R. Friborg, Søren Brandslund, Ivan Vaag, Allan Beck-Nielsen, Henning Sørensen, Henrik Toft Thomsen, Reimar Wernich |
| description | To examine the prevalence of micro- and macrovascular complications and their associated clinical characteristics at time of type 2 diabetes (T2D) diagnosis.
We examined the prevalence of complications and associated clinical characteristics among 6958 newly diagnosed T2D patients enrolled in the prospective Danish Center for Strategic Research in T2D cohort during 2010–2016. We calculated age- and gender-adjusted prevalence ratios (aPRs) of complications using log-binomial and Poisson regression.
In total, 35% (n=2456) T2D patients had diabetic complications around diagnosis; 12% (n=828) had microvascular complications, 17% (n=1186) macrovascular complications, and 6% (n=442) had both. HbA1c levels of ≥7% were associated with microvascular complications [HbA1c 7%–8%; aPR: 1.35, 95% confidence interval (CI): 1.12–1.62] but not macrovascular complications [aPR: 0.91, 95% CI: 0.76–1.08]. High C-peptide≥800pmol/L was associated with macrovascular [aPR 1.34, 95% CI: 1.00–1.80] but not microvascular [aPR 0.97, 95% CI: 0.71–1.33] complications. Macrovascular complications were associated with male sex, age>50years, obesity, hypertriglyceridemia, low HDL cholesterol, smoking, elevated CRP levels, and anti-hypertensive therapy. Microvascular complications were associated with high blood pressure, hypertriglyceridemia, and absence of lipid-lowering therapy.
One-third of patients with T2D had diabetes complications around time of diagnosis. Our findings suggest different pathophysiological mechanisms behind micro- and macrovascular complications.
•One-third (35%) of T2D patients had diabetes complications at time of diagnosis.•12% had microvascular, 17% had macrovascular, and 6% had both complications.•Poor glucose control was associated with micro- but not macrovascular complications.•High C-peptide was associated with macro- but not microvascular complications.•Our findings suggest different pathophysiology behind the two complication types. |
| doi_str_mv | 10.1016/j.jdiacomp.2017.09.010 |
| format | Article |
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We examined the prevalence of complications and associated clinical characteristics among 6958 newly diagnosed T2D patients enrolled in the prospective Danish Center for Strategic Research in T2D cohort during 2010–2016. We calculated age- and gender-adjusted prevalence ratios (aPRs) of complications using log-binomial and Poisson regression.
In total, 35% (n=2456) T2D patients had diabetic complications around diagnosis; 12% (n=828) had microvascular complications, 17% (n=1186) macrovascular complications, and 6% (n=442) had both. HbA1c levels of ≥7% were associated with microvascular complications [HbA1c 7%–8%; aPR: 1.35, 95% confidence interval (CI): 1.12–1.62] but not macrovascular complications [aPR: 0.91, 95% CI: 0.76–1.08]. High C-peptide≥800pmol/L was associated with macrovascular [aPR 1.34, 95% CI: 1.00–1.80] but not microvascular [aPR 0.97, 95% CI: 0.71–1.33] complications. Macrovascular complications were associated with male sex, age>50years, obesity, hypertriglyceridemia, low HDL cholesterol, smoking, elevated CRP levels, and anti-hypertensive therapy. Microvascular complications were associated with high blood pressure, hypertriglyceridemia, and absence of lipid-lowering therapy.
One-third of patients with T2D had diabetes complications around time of diagnosis. Our findings suggest different pathophysiological mechanisms behind micro- and macrovascular complications.
•One-third (35%) of T2D patients had diabetes complications at time of diagnosis.•12% had microvascular, 17% had macrovascular, and 6% had both complications.•Poor glucose control was associated with micro- but not macrovascular complications.•High C-peptide was associated with macro- but not microvascular complications.•Our findings suggest different pathophysiology behind the two complication types.</description><identifier>ISSN: 1056-8727</identifier><identifier>EISSN: 1873-460X</identifier><identifier>DOI: 10.1016/j.jdiacomp.2017.09.010</identifier><identifier>PMID: 29107454</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Angina pectoris ; Blood pressure ; Cardiovascular disease ; Cohort Studies ; Cross-Sectional Studies ; Delayed Diagnosis - statistics & numerical data ; Denmark - epidemiology ; Diabetes ; Diabetes Complications - epidemiology ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - diagnosis ; Diabetes Mellitus, Type 2 - epidemiology ; Diabetic Angiopathies - classification ; Diabetic Angiopathies - epidemiology ; Diabetic neuropathy ; Diabetic retinopathy ; Epidemiology ; Eye diseases ; Fasting ; Female ; Health risk assessment ; Humans ; Hyperglycemia ; Hypertension ; Kidney diseases ; Lipids ; Macrovascular complications ; Male ; Medical diagnosis ; Medical research ; Metabolic syndrome ; Microvascular complications ; Middle Aged ; Mortality ; Patients ; Peptides ; Prevalence ; Risk factors ; Time Factors ; Type 2 diabetes</subject><ispartof>Journal of diabetes and its complications, 2018-01, Vol.32 (1), p.34-40</ispartof><rights>2017 Elsevier Inc.</rights><rights>Copyright © 2017 Elsevier Inc. All rights reserved.</rights><rights>2017. Elsevier Inc.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c444t-dcadb19d3e86386adb434a3cd5b0d09c9a29da6e56f73b965adbe45c874171833</citedby><cites>FETCH-LOGICAL-c444t-dcadb19d3e86386adb434a3cd5b0d09c9a29da6e56f73b965adbe45c874171833</cites><orcidid>0000-0002-4203-5442 ; 0000-0002-7428-7898</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://www.proquest.com/docview/1983446021?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>314,780,784,3548,27923,27924,45994,64384,64386,64388,72240</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/29107454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Gedebjerg, Anne</creatorcontrib><creatorcontrib>Almdal, Thomas Peter</creatorcontrib><creatorcontrib>Berencsi, Klara</creatorcontrib><creatorcontrib>Rungby, Jørgen</creatorcontrib><creatorcontrib>Nielsen, Jens Steen</creatorcontrib><creatorcontrib>Witte, Daniel R.</creatorcontrib><creatorcontrib>Friborg, Søren</creatorcontrib><creatorcontrib>Brandslund, Ivan</creatorcontrib><creatorcontrib>Vaag, Allan</creatorcontrib><creatorcontrib>Beck-Nielsen, Henning</creatorcontrib><creatorcontrib>Sørensen, Henrik Toft</creatorcontrib><creatorcontrib>Thomsen, Reimar Wernich</creatorcontrib><title>Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort</title><title>Journal of diabetes and its complications</title><addtitle>J Diabetes Complications</addtitle><description>To examine the prevalence of micro- and macrovascular complications and their associated clinical characteristics at time of type 2 diabetes (T2D) diagnosis.
We examined the prevalence of complications and associated clinical characteristics among 6958 newly diagnosed T2D patients enrolled in the prospective Danish Center for Strategic Research in T2D cohort during 2010–2016. We calculated age- and gender-adjusted prevalence ratios (aPRs) of complications using log-binomial and Poisson regression.
In total, 35% (n=2456) T2D patients had diabetic complications around diagnosis; 12% (n=828) had microvascular complications, 17% (n=1186) macrovascular complications, and 6% (n=442) had both. HbA1c levels of ≥7% were associated with microvascular complications [HbA1c 7%–8%; aPR: 1.35, 95% confidence interval (CI): 1.12–1.62] but not macrovascular complications [aPR: 0.91, 95% CI: 0.76–1.08]. High C-peptide≥800pmol/L was associated with macrovascular [aPR 1.34, 95% CI: 1.00–1.80] but not microvascular [aPR 0.97, 95% CI: 0.71–1.33] complications. Macrovascular complications were associated with male sex, age>50years, obesity, hypertriglyceridemia, low HDL cholesterol, smoking, elevated CRP levels, and anti-hypertensive therapy. Microvascular complications were associated with high blood pressure, hypertriglyceridemia, and absence of lipid-lowering therapy.
One-third of patients with T2D had diabetes complications around time of diagnosis. Our findings suggest different pathophysiological mechanisms behind micro- and macrovascular complications.
•One-third (35%) of T2D patients had diabetes complications at time of diagnosis.•12% had microvascular, 17% had macrovascular, and 6% had both complications.•Poor glucose control was associated with micro- but not macrovascular complications.•High C-peptide was associated with macro- but not microvascular complications.•Our findings suggest different pathophysiology behind the two complication types.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Angina pectoris</subject><subject>Blood pressure</subject><subject>Cardiovascular disease</subject><subject>Cohort Studies</subject><subject>Cross-Sectional Studies</subject><subject>Delayed Diagnosis - statistics & numerical data</subject><subject>Denmark - epidemiology</subject><subject>Diabetes</subject><subject>Diabetes Complications - epidemiology</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - diagnosis</subject><subject>Diabetes Mellitus, Type 2 - epidemiology</subject><subject>Diabetic Angiopathies - classification</subject><subject>Diabetic Angiopathies - epidemiology</subject><subject>Diabetic neuropathy</subject><subject>Diabetic retinopathy</subject><subject>Epidemiology</subject><subject>Eye diseases</subject><subject>Fasting</subject><subject>Female</subject><subject>Health risk assessment</subject><subject>Humans</subject><subject>Hyperglycemia</subject><subject>Hypertension</subject><subject>Kidney diseases</subject><subject>Lipids</subject><subject>Macrovascular complications</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical research</subject><subject>Metabolic syndrome</subject><subject>Microvascular complications</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Patients</subject><subject>Peptides</subject><subject>Prevalence</subject><subject>Risk factors</subject><subject>Time Factors</subject><subject>Type 2 diabetes</subject><issn>1056-8727</issn><issn>1873-460X</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNqFkc-KFDEQxhtR3HX1FZaAFy89Jp10utuTy47_YEEPCt5COqlxMnR3xlR6YF7U57F6ZlfBixBIBX71fZX6iuJa8JXgQr_erXY-WBfH_ariolnxbsUFf1RciraRpdL8-2Oqea3Ltqmai-IZ4o5zrutaPC0uqk7wRtXqsvj1JcHBDjA5YHHDxuBSLJmdPBstlQeLbh5sYmTWQwZki-UQnM0hTshsZjmMp9Z83AOr_oJU_JgiBjypWcTogs3gmRvCRAIDc1ubrMuQAubg8A27YWSJWCK4RZ6Q3iIQDgzz7I-Lje7qlu3JHqaMLEwsb4Gt7RRwy9briubbxpSfF082dkB4cX9fFd_ev_t6-7G8-_zh0-3NXemUUrn0zvpedF5Cq2Wr6aGkstL5uueed66zVeethlpvGtl3uiYCVO3aRolGtFJeFa_OuvsUf86A2YwBHQyDnSDOaESnhZZa0rkqXv6D7uKc6JML1UpFmVWCKH2mTptIsDH7FEabjkZwsyRvduYhebMkb3hnKHlqvL6Xn_sR_J-2h6gJeHsGgPZxCJAMurDk7kOifRsfw_88fgOJ2saj</recordid><startdate>201801</startdate><enddate>201801</enddate><creator>Gedebjerg, Anne</creator><creator>Almdal, Thomas Peter</creator><creator>Berencsi, Klara</creator><creator>Rungby, Jørgen</creator><creator>Nielsen, Jens Steen</creator><creator>Witte, Daniel R.</creator><creator>Friborg, Søren</creator><creator>Brandslund, Ivan</creator><creator>Vaag, Allan</creator><creator>Beck-Nielsen, Henning</creator><creator>Sørensen, Henrik Toft</creator><creator>Thomsen, Reimar Wernich</creator><general>Elsevier Inc</general><general>Elsevier Limited</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>ASE</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FPQ</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>K6X</scope><scope>K9-</scope><scope>K9.</scope><scope>KB0</scope><scope>M0R</scope><scope>M0S</scope><scope>M1P</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>Q9U</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-4203-5442</orcidid><orcidid>https://orcid.org/0000-0002-7428-7898</orcidid></search><sort><creationdate>201801</creationdate><title>Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort</title><author>Gedebjerg, Anne ; Almdal, Thomas Peter ; Berencsi, Klara ; Rungby, Jørgen ; Nielsen, Jens Steen ; Witte, Daniel R. ; Friborg, Søren ; Brandslund, Ivan ; Vaag, Allan ; Beck-Nielsen, Henning ; Sørensen, Henrik Toft ; Thomsen, Reimar Wernich</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c444t-dcadb19d3e86386adb434a3cd5b0d09c9a29da6e56f73b965adbe45c874171833</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Angina pectoris</topic><topic>Blood pressure</topic><topic>Cardiovascular disease</topic><topic>Cohort Studies</topic><topic>Cross-Sectional Studies</topic><topic>Delayed Diagnosis - statistics & numerical data</topic><topic>Denmark - epidemiology</topic><topic>Diabetes</topic><topic>Diabetes Complications - epidemiology</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes Mellitus, Type 2 - diagnosis</topic><topic>Diabetes Mellitus, Type 2 - epidemiology</topic><topic>Diabetic Angiopathies - classification</topic><topic>Diabetic Angiopathies - epidemiology</topic><topic>Diabetic neuropathy</topic><topic>Diabetic retinopathy</topic><topic>Epidemiology</topic><topic>Eye diseases</topic><topic>Fasting</topic><topic>Female</topic><topic>Health risk assessment</topic><topic>Humans</topic><topic>Hyperglycemia</topic><topic>Hypertension</topic><topic>Kidney diseases</topic><topic>Lipids</topic><topic>Macrovascular complications</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical research</topic><topic>Metabolic syndrome</topic><topic>Microvascular complications</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Patients</topic><topic>Peptides</topic><topic>Prevalence</topic><topic>Risk factors</topic><topic>Time Factors</topic><topic>Type 2 diabetes</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Gedebjerg, Anne</creatorcontrib><creatorcontrib>Almdal, Thomas Peter</creatorcontrib><creatorcontrib>Berencsi, Klara</creatorcontrib><creatorcontrib>Rungby, Jørgen</creatorcontrib><creatorcontrib>Nielsen, Jens Steen</creatorcontrib><creatorcontrib>Witte, Daniel R.</creatorcontrib><creatorcontrib>Friborg, Søren</creatorcontrib><creatorcontrib>Brandslund, Ivan</creatorcontrib><creatorcontrib>Vaag, Allan</creatorcontrib><creatorcontrib>Beck-Nielsen, Henning</creatorcontrib><creatorcontrib>Sørensen, Henrik Toft</creatorcontrib><creatorcontrib>Thomsen, Reimar Wernich</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>ProQuest Nursing & Allied Health Database</collection><collection>Health & Medical Collection (Proquest)</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>British Nursing Database</collection><collection>British Nursing Index</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central</collection><collection>British Nursing Index (BNI) (1985 to Present)</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>British Nursing Index</collection><collection>Consumer Health Database (Alumni Edition)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Consumer Database (Proquest)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of diabetes and its complications</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Gedebjerg, Anne</au><au>Almdal, Thomas Peter</au><au>Berencsi, Klara</au><au>Rungby, Jørgen</au><au>Nielsen, Jens Steen</au><au>Witte, Daniel R.</au><au>Friborg, Søren</au><au>Brandslund, Ivan</au><au>Vaag, Allan</au><au>Beck-Nielsen, Henning</au><au>Sørensen, Henrik Toft</au><au>Thomsen, Reimar Wernich</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort</atitle><jtitle>Journal of diabetes and its complications</jtitle><addtitle>J Diabetes Complications</addtitle><date>2018-01</date><risdate>2018</risdate><volume>32</volume><issue>1</issue><spage>34</spage><epage>40</epage><pages>34-40</pages><issn>1056-8727</issn><eissn>1873-460X</eissn><abstract>To examine the prevalence of micro- and macrovascular complications and their associated clinical characteristics at time of type 2 diabetes (T2D) diagnosis.
We examined the prevalence of complications and associated clinical characteristics among 6958 newly diagnosed T2D patients enrolled in the prospective Danish Center for Strategic Research in T2D cohort during 2010–2016. We calculated age- and gender-adjusted prevalence ratios (aPRs) of complications using log-binomial and Poisson regression.
In total, 35% (n=2456) T2D patients had diabetic complications around diagnosis; 12% (n=828) had microvascular complications, 17% (n=1186) macrovascular complications, and 6% (n=442) had both. HbA1c levels of ≥7% were associated with microvascular complications [HbA1c 7%–8%; aPR: 1.35, 95% confidence interval (CI): 1.12–1.62] but not macrovascular complications [aPR: 0.91, 95% CI: 0.76–1.08]. High C-peptide≥800pmol/L was associated with macrovascular [aPR 1.34, 95% CI: 1.00–1.80] but not microvascular [aPR 0.97, 95% CI: 0.71–1.33] complications. Macrovascular complications were associated with male sex, age>50years, obesity, hypertriglyceridemia, low HDL cholesterol, smoking, elevated CRP levels, and anti-hypertensive therapy. Microvascular complications were associated with high blood pressure, hypertriglyceridemia, and absence of lipid-lowering therapy.
One-third of patients with T2D had diabetes complications around time of diagnosis. Our findings suggest different pathophysiological mechanisms behind micro- and macrovascular complications.
•One-third (35%) of T2D patients had diabetes complications at time of diagnosis.•12% had microvascular, 17% had macrovascular, and 6% had both complications.•Poor glucose control was associated with micro- but not macrovascular complications.•High C-peptide was associated with macro- but not microvascular complications.•Our findings suggest different pathophysiology behind the two complication types.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>29107454</pmid><doi>10.1016/j.jdiacomp.2017.09.010</doi><tpages>7</tpages><orcidid>https://orcid.org/0000-0002-4203-5442</orcidid><orcidid>https://orcid.org/0000-0002-7428-7898</orcidid><oa>free_for_read</oa></addata></record> |
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| identifier | ISSN: 1056-8727 |
| ispartof | Journal of diabetes and its complications, 2018-01, Vol.32 (1), p.34-40 |
| issn | 1056-8727 1873-460X |
| language | eng |
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| source | MEDLINE; ScienceDirect Freedom Collection (Elsevier); ProQuest Central |
| subjects | Adult Aged Aged, 80 and over Angina pectoris Blood pressure Cardiovascular disease Cohort Studies Cross-Sectional Studies Delayed Diagnosis - statistics & numerical data Denmark - epidemiology Diabetes Diabetes Complications - epidemiology Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - epidemiology Diabetic Angiopathies - classification Diabetic Angiopathies - epidemiology Diabetic neuropathy Diabetic retinopathy Epidemiology Eye diseases Fasting Female Health risk assessment Humans Hyperglycemia Hypertension Kidney diseases Lipids Macrovascular complications Male Medical diagnosis Medical research Metabolic syndrome Microvascular complications Middle Aged Mortality Patients Peptides Prevalence Risk factors Time Factors Type 2 diabetes |
| title | Prevalence of micro- and macrovascular diabetes complications at time of type 2 diabetes diagnosis and associated clinical characteristics: A cross-sectional baseline study of 6958 patients in the Danish DD2 cohort |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-10T17%3A51%3A24IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Prevalence%20of%20micro-%20and%20macrovascular%20diabetes%20complications%20at%20time%20of%20type%202%20diabetes%20diagnosis%20and%20associated%20clinical%20characteristics:%20A%20cross-sectional%20baseline%20study%20of%206958%20patients%20in%20the%20Danish%20DD2%20cohort&rft.jtitle=Journal%20of%20diabetes%20and%20its%20complications&rft.au=Gedebjerg,%20Anne&rft.date=2018-01&rft.volume=32&rft.issue=1&rft.spage=34&rft.epage=40&rft.pages=34-40&rft.issn=1056-8727&rft.eissn=1873-460X&rft_id=info:doi/10.1016/j.jdiacomp.2017.09.010&rft_dat=%3Cproquest_cross%3E1961636336%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=1983446021&rft_id=info:pmid/29107454&rft_els_id=S1056872717308991&rfr_iscdi=true |