Increased 8-isoprostane, a Marker of Oxidative Stress in Exhaled Breath Condensate in Subjects with Asbestos Exposure

Asbestosis and pleural plaques exhibit unpredictable but progressive development, and there are no markers routinely available to measure their prognosis. Asbestos exposure induces the generation of reactive oxygen species, and 8-isoprostane is involved in experimental asbestos-related lung toxicity...

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Veröffentlicht in:	Industrial Health 2008, Vol.46(5), pp.484-489
Hauptverfasser:	PELCLOVÁ, Daniela, FENCLOVÁ, Zdenka, KAČER, Petr, KUZMA, Marek, NAVRÁTIL, Tomáš, LEBEDOVÁ, Jindřiška
Format:	Artikel
Sprache:	eng
Schlagworte:	8-isoprostane Aged Aged, 80 and over Asbestos Asbestos - metabolism Asbestos - poisoning Asbestosis Asbestosis - metabolism Biomarkers - analysis Breath condensate Breath Tests - methods Case-Control Studies Cotinine Dinoprost - analogs & derivatives Dinoprost - analysis Dinoprost - metabolism Female Humans Male Middle Aged Occupational Exposure Oxidative Stress Pleural hyalinosis Prognosis Rheumatoid factor Risk Assessment α1-antitrypsin α1-microglobulin
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